Gene Symbol | AGAP1 |
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Entrez Gene | 116987 |
Alt Symbol | AGAP-1, CENTG2, GGAP1, cnt-g2 |
Species | Human |
Gene Type | protein-coding |
Description | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 |
Other Description | Arf GAP with GTP-binding protein-like, ANK repeat and PH domains 1|GTP-binding and GTPase-activating protein 1|arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1|centaurin, gamma 2 |
Swissprots | Q9NV93 B2RTX7 Q541S5 Q9UPQ3 Q6P9D7 |
Accessions | AAX88852 AAX88857 AAY14697 AAY24137 EAW71078 EAW71079 Q9UPQ3 AB029022 BAA83051 AF413078 AAL04172 AK001722 BAA91862 AK295520 BAG58435 AK300763 BAG62428 AY033765 AAK56506 BC060814 AAH60814 BC140856 AAI40857 BC167153 AAI67153 BC167157 AAI67157 BI868924 BM752978 CA446024 CB961699 DQ570804 DQ584637 KJ534764 AHW56404 XM_005246059 XP_005246116 XM_006712234 XP_006712297 XM_006712235 XP_006712298 XM_006712237 XP_006712300 XM_006712239 XP_006712302 XM_011510547 XP_011508849 XM_011510548 XP_011508850 XM_011510549 XP_011508851 NM_001037131 NP_001032208 NM_001244888 NP_001231817 NM_014914 NP_055729 |
Function | GTPase-activating protein for ARF1 and, to a lesser extent, ARF5. Directly and specifically regulates the adapter protein 3 (AP-3)-dependent trafficking of proteins in the endosomal-lysosomal system. {ECO:0000269|PubMed:12640130}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:12388557, ECO:0000269|PubMed:12640130}. Note=Associates with the endocytic compartment. |
Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:12388557, ECO:0000269|PubMed:12640130, ECO:0000269|PubMed:15381706, ECO:0000269|PubMed:16079295}. |
Top Pathways | Endocytosis |
Human AGAP1 full length protein - ab131978 from Abcam
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Human AGAP1 peptide - ab23095 from Abcam
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CENTG2 / AGAP1 Antibody Blocking Peptide - LS-E25573 from LifeSpan Bioscience
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CENTG2 / AGAP1 Antibody Blocking Peptide - LS-E22655 from LifeSpan Bioscience
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Recombinant Human AGAP1 Protein - H00116987-P01 from Novus Biologicals
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Recombinant Human AGAP1 Protein - H00116987-Q01 from Novus Biologicals
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AGAP1-Antibody-N-term-Blocking-Peptide - BP16814a from Abgent, a WuXi AppTec company
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AGAP1 Peptide - AC21-0402-P from Abcore
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AGAP1 / CENTG2 - H00116987-P01-10 from Acris Antibodies
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AGAP1 / CENTG2 - H00116987-P01-25 from Acris Antibodies
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AGAP1 / CENTG2 - H00116987-Q01-10 from Acris Antibodies
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AGAP1 / CENTG2 - H00116987-Q01-25 from Acris Antibodies
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AGAP1 Peptide - 45-213P from ProSci
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AGAP1,CENTG2 fusion protein - Ag6846 from Proteintech Group
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AGAP1,CENTG2 fusion protein - ag5362 from Proteintech Group
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Recombinant Human AGAP1, His-tagged - AGAP1-26447TH from Creative Biomart
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Recombinant Human Arf-GAP with GTPase, ANK repeat and PH domain-containing prote - CSB-YP890774HU CSB-EP890774HU CSB-BP890774HU CSB-MP890774HU from Cusabio
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AGAP1 / CENTG2 (transcript variant 2) - TP314836 from Acris Antibodies
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Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1(AGAP1) ,partial, Recombinant Protein - MBS1430808 from MyBioSource
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CENTG2/AGAP1, Peptide - MBS425165 from MyBioSource
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AGAP1 Peptide, Human - M34GP00358H from Creative Peptides
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AGAP1 Recombinant Protein Antigen - NBP2-49005PEP from Novus Biologicals
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CENTG2 Immunizing peptide - orb17171 from Biorbyt
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