TBC1D2

Gene Symbol TBC1D2
Entrez Gene 55357
Alt Symbol PARIS-1, PARIS1, TBC1D2A
Species Human
Gene Type protein-coding
Description TBC1 domain family, member 2
Other Description TBC1 domain family member 2A|TBC1 domain family, member 2A|armus|prostate antigen recognized and identified by SEREX 1
Swissprots Q59EU0 Q9BYX2 Q9NSH4 Q8WYT1 B9A6J7 Q9H6A2 B3KWD1 B4DQ05 Q5TBQ5 Q6IPC7 Q7L1K8
Accessions EAW58882 EAW58883 EAW58884 EAW58885 EAW58886 EAW58887 EAW58888 Q9BYX2 AB209721 BAD92958 AB449882 BAH16625 AF318370 AAL55877 AK026105 BAB15361 AK124772 BAG54093 AK131290 BAG54761 AK298575 BAG60767 AL353935 CAB89247 AY026527 AAK07684 BC028918 AAH28918 BC071978 AAH71978 BX091503 DB167423 DQ891305 ABM82231 DQ894490 ABM85416 XM_011518843 XP_011517145 XM_011518844 XP_011517146 XR_929823 XR_929824 NM_001267571 NP_001254500 NM_001267572 NP_001254501 NM_018421 NP_060891 NR_051978
Function Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion. {ECO:0000269|PubMed:20116244}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20116244}. Cytoplasmic vesicle {ECO:0000269|PubMed:20116244}. Cell junction {ECO:0000269|PubMed:20116244}.
Tissue Specificity Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level). {ECO:0000269|PubMed:11785977, ECO:0000269|PubMed:20116244}.

TBC1D2 (Q-14) - sc-137818 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
TBC1D2 (Q-14): sc-137818. Western blot analysis of TBC1D2 expression in non-transfected 293T: sc-117752 (A), human TBC1D2 transfected 293T: sc-113919 (B), I-11.15 (C) and DU 145 (D) whole cell lysates.

TBC1D2 (E-12) - sc-137817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-TBC1D2 antibody - ab200692 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TBC1D2 antibody (ab200692)Lane 1 : MCF7 whole cell lysateLane 2 : sp2/0 whole cell lysateLane 3 : PC12 whole cell lysate

Anti-TBC1D2 antibody - ab68728 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-TBC1D2 antibody (ab68728) at 1/500 dilution + lysate from human spleen at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-TBC1D2 antibody - N-terminal - ab176701 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-TBC1D2 antibody - N-terminal (ab176701) at 0.04 µg/mlLane 1 : HeLa whole cell lysate at 50 µgLane 2 : HeLa whole cell lysate at 15 µgLane 3 : 293T whole cell lysate at 50 µgLane 4 : Jurkat whole cell lysate at 50 µgdeveloped using the ECL technique

Anti-TBC1D2 Antibody (aa438-465, APC) - LS-C271051 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465, AP) - LS-C271050 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465, Biotin) - LS-C271052 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465, FITC) - LS-C271053 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465, Azide-free, HRP) - LS-C271054 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465, PE) - LS-C271059 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa1-50) - LS-C290115 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa225-275) - LS-C290116 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa878-928) - LS-C290117 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa437-465) - LS-C325592 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-TBC1D2 Antibody (aa438-465) - LS-C157145 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
TBC1D2 Antibody western blot of mouse testis tissue lysates (35 ug/lane). The TBC1D2 antibody detected the TBC1D2 protein (arrow).

TBC1D2 Antibody - NBP1-87335 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: TBC1D2 Antibody [NBP1-87335] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-569

TBC1D2 Antibody - H00055357-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: TBC1D2 Antibody [H00055357-B01P] - Analysis of TBC1D2 expression in human spleen.

TBC1D2 Antibody - NBP1-79030 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: TBC1D2 Antibody [NBP1-79030] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-TBC1D2 antibody used for IP at 6 mcg/mg lysate. TBC1D2 was also immunoprecipitated by rabbit anti-TBC1D2 antibodies NBP1-79028 and NBP1-79030, which recognize upstream epitopes.

TBC1D2 Antibody - NBP1-79028 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

TBC1D2 Antibody - NBP1-79029 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunoprecipitation: TBC1D2 Antibody [NBP1-79029] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-TBC1D2 antibody used for IP at 6 mcg/mg lysate. TBC1D2 was also immunoprecipitated by rabbit anti-TBC1D2 antibodies NBP1-79028 and, which recognize other epitopes.

Anti-TBC1D2 antibody produced in rabbit - HPA030871 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-TBC1D2: <B>Cat. No. HPA030871</B>: Immunohistochemical staining of human esophagus shows moderate cytoplasmic and nucleolar positivity in squamous epithelial cells.

Anti-TBC1D2 antibody produced in mouse - SAB1400614 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-TBC1D2, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1400614</B>: Antibody concentration: 1.0 ~ 5.0 μg/mL. Specific band of ~104.2 kDa using human spleen lysate.

TBC1D2-Antibody-Center - AP18590c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
TBC1D2 Antibody (Center) (Cat. #AP18590c) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the TBC1D2 antibody detected the TBC1D2 protein (arrow).

TBC1D2 Antibody - middle region (OAAB14132) - OAAB14132 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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