TBC1D2

Gene Symbol TBC1D2
Entrez Gene 55357
Alt Symbol PARIS-1, PARIS1, TBC1D2A
Species Human
Gene Type protein-coding
Description TBC1 domain family, member 2
Other Description TBC1 domain family member 2A|TBC1 domain family, member 2A|armus|prostate antigen recognized and identified by SEREX 1
Swissprots Q59EU0 Q9BYX2 Q9NSH4 Q8WYT1 B9A6J7 Q9H6A2 B3KWD1 B4DQ05 Q5TBQ5 Q6IPC7 Q7L1K8
Accessions EAW58882 EAW58883 EAW58884 EAW58885 EAW58886 EAW58887 EAW58888 Q9BYX2 AB209721 BAD92958 AB449882 BAH16625 AF318370 AAL55877 AK026105 BAB15361 AK124772 BAG54093 AK131290 BAG54761 AK298575 BAG60767 AL353935 CAB89247 AY026527 AAK07684 BC028918 AAH28918 BC071978 AAH71978 BX091503 DB167423 DQ891305 ABM82231 DQ894490 ABM85416 XM_011518843 XP_011517145 XM_011518844 XP_011517146 XR_929823 XR_929824 NM_001267571 NP_001254500 NM_001267572 NP_001254501 NM_018421 NP_060891 NR_051978
Function Acts as GTPase-activating protein for RAB7A. Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and subsequent inhibition of cadherin degradation and reduced cell-cell adhesion. {ECO:0000269|PubMed:20116244}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:20116244}. Cytoplasmic vesicle {ECO:0000269|PubMed:20116244}. Cell junction {ECO:0000269|PubMed:20116244}.
Tissue Specificity Expressed in a broad range of tissues, especially in kidney, liver, lung and placenta. Also expressed in keratinocytes and epithelia-containing organs. Isoform 2 is differentially expressed in prostate normal and cancer cells (at protein level). {ECO:0000269|PubMed:11785977, ECO:0000269|PubMed:20116244}.

TBC1D2 CRISPR/Cas9 KO Plasmid (h) - sc-412529 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 HDR Plasmid (h) - sc-412529-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 Double Nickase Plasmid (h) - sc-412529-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 Double Nickase Plasmid (h2) - sc-412529-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 CRISPR Activation Plasmid (h) - sc-412529-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 CRISPR Activation Plasmid (h2) - sc-412529-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 Lentiviral Activation Particles (h) - sc-412529-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 Lentiviral Activation Particles (h2) - sc-412529-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

TBC1D2 siRNA (h) - sc-92736 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBC1D2 shRNA Plasmid (h) - sc-92736-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

TBC1D2 shRNA (h) Lentiviral Particles - sc-92736-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU139611 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN21056 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21056 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03547 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03547

TBC1D2 siRNA (Human) - CRJ0685 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBC1D2 - MBS8212090 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human TBC1D2 (NM_018421.3) - SHH423852 from Creative biogene

Category siRNA
Species Reactivities Human

Human TBC1D2 siRNA - orb271186 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

TBC1D2 shRNA Plasmid (Human) - CHJ0685 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

TBC1D2 miRNA 3'UTR clone - MiUTR3H-10865 from Creative biogene

Species Reactivities Human
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