DNASE1L2

Gene Symbol DNASE1L2
Entrez Gene 1775
Alt Symbol DNAS1L2
Species Human
Gene Type protein-coding
Description deoxyribonuclease I-like 2
Other Description DNase I homolog protein DHP1|DNase I-like 2|deoxyribonuclease-1-like 2
Swissprots E9PBY4 Q6JVM3 Q6JVM2 Q92874
Accessions AAQ73760 AAQ73761 EAW85526 EAW85527 EAW85528 EAW85529 Q92874 AK098028 BAG53566 AY298957 AAQ73759 BC035205 AAH35205 BC063710 AAH63710 U62647 AAB63981 XM_011522399 XP_011520701 NM_001301680 NP_001288609 NM_001374 NP_001365
Function Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells. {ECO:0000269|PubMed:16902420}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:16902420}. Secreted {ECO:0000305}.
Tissue Specificity Preferentially expressed in the skin and up- regulated during keratinocytes differentiation. Highly abundant (at protein level) in the stratum granulosum. {ECO:0000269|PubMed:16902420}.

DNASE1L2 CRISPR/Cas9 KO Plasmid (h) - sc-408725 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 HDR Plasmid (h) - sc-408725-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 Double Nickase Plasmid (h) - sc-408725-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 Double Nickase Plasmid (h2) - sc-408725-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 CRISPR Activation Plasmid (h) - sc-408725-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 CRISPR Activation Plasmid (h2) - sc-408725-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 Lentiviral Activation Particles (h) - sc-408725-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 Lentiviral Activation Particles (h2) - sc-408725-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

DNASE1L2 siRNA (h) - sc-77320 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNASE1L2 shRNA Plasmid (h) - sc-77320-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

DNASE1L2 shRNA (h) Lentiviral Particles - sc-77320-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU120221 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7390 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7390 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

DNASE1L2 siRNA (Human) - CRH1233 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNASE1L2 RNAi - H00001775-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

DNASE1L2 - MBS8204934 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human DNASE1L2 (NM_001374.2) - SHH279809 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human DNASE1L2(NM_001374.2) - SHH011603 from Creative biogene

Category siRNA
Species Reactivities Human

Human DNASE1L2 siRNA - orb261735 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

DNASE1L2 shRNA Plasmid (Human) - CHH1233 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

DNASE1L2 miRNA 3'UTR clone - MiUTR1H-02933 from Creative biogene

Species Reactivities Human
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