Gene Symbol | DNASE1L2 |
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Entrez Gene | 1775 |
Alt Symbol | DNAS1L2 |
Species | Human |
Gene Type | protein-coding |
Description | deoxyribonuclease I-like 2 |
Other Description | DNase I homolog protein DHP1|DNase I-like 2|deoxyribonuclease-1-like 2 |
Swissprots | E9PBY4 Q6JVM3 Q6JVM2 Q92874 |
Accessions | AAQ73760 AAQ73761 EAW85526 EAW85527 EAW85528 EAW85529 Q92874 AK098028 BAG53566 AY298957 AAQ73759 BC035205 AAH35205 BC063710 AAH63710 U62647 AAB63981 XM_011522399 XP_011520701 NM_001301680 NP_001288609 NM_001374 NP_001365 |
Function | Divalent cation-dependent acid DNA endonuclease involved in the breakdown of the nucleus during corneocyte formation of epidermal keratinocytes. May play an immune role by eliminating harmful DNA released into the extracellular environment by damaged epidermal cells. {ECO:0000269|PubMed:16902420}. |
Subcellular Location | Cytoplasm {ECO:0000269|PubMed:16902420}. Secreted {ECO:0000305}. |
Tissue Specificity | Preferentially expressed in the skin and up- regulated during keratinocytes differentiation. Highly abundant (at protein level) in the stratum granulosum. {ECO:0000269|PubMed:16902420}. |
DNASE1L2 (A-14) - sc-68312 from Santa Cruz Biotechnology
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DNASE1L2 (C-19) - sc-68313 from Santa Cruz Biotechnology
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Anti-DNASE1L2 antibody - ab126476 from Abcam
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Anti-DNASE1L2 Antibody (aa166-215) - LS-C206280 from LifeSpan Bioscience
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Anti-DNASE1L2 Antibody (aa32-229) - LS-C293670 from LifeSpan Bioscience
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Anti-DNASE1L2 Antibody (aa28-232) - LS-C314429 from LifeSpan Bioscience
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Anti-DNASE1L2 Antibody (aa32-229, FITC) - LS-C302394 from LifeSpan Bioscience
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Anti-DNASE1L2 Antibody (aa32-229, Biotin) - LS-C298237 from LifeSpan Bioscience
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DNASE1L2 Antibody - NBP1-91429 from Novus Biologicals
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DNASE1L2 Antibody - NBP1-91844 from Novus Biologicals
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Anti-DNASE1L2 antibody produced in rabbit - HPA044714 from Sigma-Aldrich
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DNASE1L2 antibody (FITC) - orb187484 from Biorbyt
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DNASE1L2 antibody - 17386-1-AP from Proteintech Group
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DNASE1L2 Antibody - EPP12374 from Elabscience
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Polyclonal Antibody to Deoxyribonuclease I Like Protein 2 (DNASE1L2) - PAA202Mu01 from Uscn Life Science Inc.
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Polyclonal Antibody to Deoxyribonuclease I Like Protein 2 (DNASE1L2) - PAA202Ra01 from Uscn Life Science Inc.
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Anti-DNASE1L2 (aa 238-287) polyclonal antibody - DPABH-22830 from Creative Diagnostics
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DNASE1L2, Polyclonal Antibody - MBS2521956 from MyBioSource
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DNASE1L2-Antibody-C-Term - AP21923b from Abgent, a WuXi AppTec company
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DNASE1L2 Antibody / Deoxyribonuclease-1-like 2 (F53838) - F53838 from NSJ Bioreagent
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DNASE1L2 Antibody - 46554 from Signalway Antibody
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DNASE1L2 Antibody - 61-160 from ProSci
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DNASE1L2, Polyclonal Antibody - MBS9217010 from MyBioSource
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Anti-DNASE1L2 Antibody (aa28-232, FITC) - LS-C418701 from LifeSpan Bioscience
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Anti-DNASE1L2 Antibody (aa28-232, Biotin) - LS-C418702 from LifeSpan Bioscience
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