IGF1

Gene Symbol	IGF1
Entrez Gene	3479
Alt Symbol	IGF-I, IGF1A, IGFI
Species	Human
Gene Type	protein-coding
Description	insulin-like growth factor 1 (somatomedin C)
Other Description	IGF-IA|IGF-IB|MGF|insulin-like growth factor I|insulin-like growth factor IA|insulin-like growth factor IB|mechano growth factor|somatomedin-C
Swissprots	Q14620 P01343 B2RWM7 P05019 E9PD02
Accessions	AAA52537 AAA52538 AAA52788 AAA52790 AAB21519 AAO74829 AAV40833 CAA27152 CAA27153 CAA27154 CAA27250 CAY39134 EAW97695 EAW97696 EAW97697 EAW97698 P05019 AB209184 BAD92421 AK312231 BAG35164 BC148266 AAI48267 BC152321 AAI52322 BC160082 AAI60082 CR541861 CAG46659 M11568 AAA52539 M27544 AAA52787 M29644 AAA52543 M37484 AAA52789 U40870 AAA96152 X00173 CAA24998 X56773 CAA40092 X56774 CAA40093 X57025 CAA40342 XR_944534 XR_944535 XR_944536 NM_000618 NP_000609 NM_001111283 NP_001104753 NM_001111284 NP_001104754 NM_001111285 NP_001104755
Function	The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. {ECO:0000269|PubMed:21076856, ECO:0000269|PubMed:24132240}.
Subcellular Location	Secreted.
Top Pathways	Focal adhesion, Rap1 signaling pathway, Long-term depression, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

IGF1-Over-expression-Lysate - LY10402a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

IGF1 overexpression lysate - LY426359 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

IGF1 293 Cell Lysate - 400274 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

IGF-I Overexpression Lysate (Native) - NBL1-11866 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

IGF-I Overexpression Lysate (Native) - NBP2-09381 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

IGF1 Over-expression Lysate Product - GWB-17A2B3 from Genway Biotech Category Cell Lysate Prices $445.00 Sizes 100 µg Species Human

Panoply™ Human IGF1 Knockdown Stable Cell Line - CSC-DC007476 from Creative biogene Category Cell Line Species Human

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