IGF1

Gene Symbol	IGF1
Entrez Gene	3479
Alt Symbol	IGF-I, IGF1A, IGFI
Species	Human
Gene Type	protein-coding
Description	insulin-like growth factor 1 (somatomedin C)
Other Description	IGF-IA|IGF-IB|MGF|insulin-like growth factor I|insulin-like growth factor IA|insulin-like growth factor IB|mechano growth factor|somatomedin-C
Swissprots	Q14620 P01343 B2RWM7 P05019 E9PD02
Accessions	AAA52537 AAA52538 AAA52788 AAA52790 AAB21519 AAO74829 AAV40833 CAA27152 CAA27153 CAA27154 CAA27250 CAY39134 EAW97695 EAW97696 EAW97697 EAW97698 P05019 AB209184 BAD92421 AK312231 BAG35164 BC148266 AAI48267 BC152321 AAI52322 BC160082 AAI60082 CR541861 CAG46659 M11568 AAA52539 M27544 AAA52787 M29644 AAA52543 M37484 AAA52789 U40870 AAA96152 X00173 CAA24998 X56773 CAA40092 X56774 CAA40093 X57025 CAA40342 XR_944534 XR_944535 XR_944536 NM_000618 NP_000609 NM_001111283 NP_001104753 NM_001111284 NP_001104754 NM_001111285 NP_001104755
Function	The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake. May play a role in synapse maturation. {ECO:0000269|PubMed:21076856, ECO:0000269|PubMed:24132240}.
Subcellular Location	Secreted.
Top Pathways	Focal adhesion, Rap1 signaling pathway, Long-term depression, Proteoglycans in cancer, Signaling pathways regulating pluripotency of stem cells

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human IGF1 full length protein - ab155614 from Abcam Category Protein Prices $239.00 Sizes 100 µg Source HEK 293 cells Species Human

Active human IGF1 full length protein - ab119455 from Abcam Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

Active human IGF1 full length protein - ab123776 from Abcam Category Protein Prices $192.00 Sizes 100 µg Source E. coli Species Human

Active human IGF1 full length protein - ab179507 from Abcam Category Protein Prices $202.00, $434.00 Sizes 100 µg, 1 mg Source E. coli Species Human

Active human IGF1 full length protein - ab9573 from Abcam Category Protein Prices $110.00, $316.00 Sizes 100 µg, 500 µg Source E. coli Species Human

Active human IGF1 full length protein - ab191621 from Abcam Category Protein Prices $192.00 Sizes 100 µg Source E. coli Species Human

Active human IGF1 protein fragment - ab73455 from Abcam Category Protein Prices $200.00 Sizes 100 µg Source E. coli Species Human

Active human IGF1 protein fragment - ab73457 from Abcam Category Protein Prices $200.00 Sizes 100 µg Source E. coli Species Human

Active human R3 IGF1 full length protein - ab58738 from Abcam Category Protein Prices $473.00 Sizes 100 µg Source E. coli Species Human

Active human R3 IGF1 full length protein - ab58750 from Abcam Category Protein Prices $157.00 Sizes 100 µg Source E. coli Species Human

Active IGF1 full length protein - ab73850 from Abcam Category Protein Prices $210.00 Sizes 10 µg Source E. coli

Active mouse IGF1 full length protein - ab198569 from Abcam Category Protein Prices $300.00, $1,089.00 Sizes 50 µg, 500 µg Source E. coli Species Mouse

Active mouse IGF1 full length protein - ab73458 from Abcam Category Protein Prices $200.00 Sizes 50 µg Source E. coli Species Mouse

Active mouse IGF1 protein fragment - ab9861 from Abcam Category Protein Prices $110.00, $257.00 Sizes 10 µg, 50 µg Source E. coli Species Mouse

Active rat IGF1 full length protein - ab198570 from Abcam Category Protein Prices $300.00, $1,089.00 Sizes 50 µg, 500 µg Source E. coli Species Rat

Active rat IGF1 full length protein - ab191786 from Abcam Category Protein Prices $192.00 Sizes 50 µg Source E. coli Species Rat

Active rat IGF1 full length protein - ab73459 from Abcam Category Protein Prices $200.00 Sizes 50 µg Source E. coli Species Rat

Cow IGF1 full length protein - ab128524 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Yeast Species Bovine

Dog IGF1 full length protein - ab169714 from Abcam Category Protein Prices $235.00 Sizes 25 µg Source Yeast Species Dog

Human IGF1 full length protein - ab87177 from Abcam Category Protein Source E. coli Species Human

IGF1 full length protein - ab101328 from Abcam Category Protein Source Yeast

Rat IGF1 full length protein - ab52006 from Abcam Category Protein Source E. coli Species Rat

IGF1 Antibody Blocking Peptide - LS-E2966 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human IGF-I Protein - NBP2-35000 from Novus Biologicals Category Protein Prices $69.00, $169.00, $199.00 Sizes 20 µg, 100 µg, 1 mg Source E. coli Species Human

Recombinant Human IGF-I 15N Protein - NBP2-35896 from Novus Biologicals Category Protein Prices $69.00, $169.00 Sizes 10 µg, 50 µg Source E. coli Species Human

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