BRAP

Gene Symbol	BRAP
Entrez Gene	8315
Alt Symbol	BRAP2, IMP, RNF52
Species	Human
Gene Type	protein-coding
Description	BRCA1 associated protein
Other Description	BRCA1-associated protein|RING finger protein 52|galectin-2-binding protein|impedes mitogenic signal propagation|renal carcinoma antigen NY-REN-63
Swissprots	O43238 B4DRM1 O75341 Q7Z569 B9EGS8
Accessions	EAW97972 Q7Z569 AB208878 BAD92115 AF035620 AAC24200 AF035950 AAB88538 AK290379 BAF83068 AK299326 BAG61333 AK308279 AY332222 AAP93638 BC136698 AAI36699 BC136699 AAI36700 BU674276 DB460078 XM_005253944 XP_005254001 XM_011538788 XP_011537090 XM_011538789 XP_011537091 NM_006768 NP_006759
Function	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. {ECO:0000269|PubMed:14724641, ECO:0000303|PubMed:10777491}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9497340}.
Tissue Specificity	Expressed in breast epithelial cell lines. {ECO:0000269|PubMed:9497340}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

BRAP (D-5) - sc-166012 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Mouse Clonality Monoclonal

BRAP (H-300) - sc-98289 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Rabbit Clonality Polyclonal

BRAP (N-12) - sc-109221 from Santa Cruz Biotechnology Prices $279.00 Sizes 200 µg/ml Host Goat Clonality Polyclonal

Anti-BRAP antibody - ab77721 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BRAP antibody - ab95179 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BRAP antibody - N-terminal - ab156605 from Abcam Prices $359.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa620-632) - LS-C3233 from LifeSpan Bioscience Prices $265.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody - LS-C12173 from LifeSpan Bioscience Prices $415.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, Azide-free, HRP) - LS-C252666 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, Biotin) - LS-C252664 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, AP) - LS-C252662 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, FITC) - LS-C252665 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, APC) - LS-C252663 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95, PE) - LS-C252667 from LifeSpan Bioscience Prices $545.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa560-592) - LS-C289402 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95) - LS-C319868 from LifeSpan Bioscience Prices $345.00 Sizes 200 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa510-560) - LS-C289403 from LifeSpan Bioscience Prices $375.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (C-Terminus) - LS-C110753 from LifeSpan Bioscience Prices $365.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa66-95) - LS-C157585 from LifeSpan Bioscience Prices $295.00 Sizes 400 µl Host Rabbit Clonality Polyclonal

Anti-BRAP2 Antibody (aa67-79) IHC-plus™ - LS-B3402 from LifeSpan Bioscience Prices $395.00 Sizes 50 µg Host Rabbit Clonality Polyclonal

Anti-BRAP antibody produced in rabbit - HPA040357 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-BRCA1-Associated Protein, BRAP2 (IMP) antibody produced in rabbit - B3810 from Sigma-Aldrich Prices $382.50 Sizes 100 µg Host Rabbit Clonality Polyclonal

BRAP antibody - middle region (ARP43079_P050) - ARP43079_P050 from Aviva Systems Biology Prices $289.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

BRAP-AntibodyN-term - AP19664a from Abgent, a WuXi AppTec company Prices $99.00, $295.00 Sizes 80 µl, 400 µl Host Rabbit Clonality Polyclonal

BRAP antibody - GTX85807 from GeneTex Prices $289.00 Sizes 25 μg Host Rabbit Clonality Polyclonal

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