BRAP

Gene Symbol	BRAP
Entrez Gene	8315
Alt Symbol	BRAP2, IMP, RNF52
Species	Human
Gene Type	protein-coding
Description	BRCA1 associated protein
Other Description	BRCA1-associated protein|RING finger protein 52|galectin-2-binding protein|impedes mitogenic signal propagation|renal carcinoma antigen NY-REN-63
Swissprots	O43238 B4DRM1 O75341 Q7Z569 B9EGS8
Accessions	EAW97972 Q7Z569 AB208878 BAD92115 AF035620 AAC24200 AF035950 AAB88538 AK290379 BAF83068 AK299326 BAG61333 AK308279 AY332222 AAP93638 BC136698 AAI36699 BC136699 AAI36700 BU674276 DB460078 XM_005253944 XP_005254001 XM_011538788 XP_011537090 XM_011538789 XP_011537091 NM_006768 NP_006759
Function	Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. {ECO:0000269|PubMed:14724641, ECO:0000303|PubMed:10777491}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:9497340}.
Tissue Specificity	Expressed in breast epithelial cell lines. {ECO:0000269|PubMed:9497340}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• Cell/Tissue/Blood Products

BRAP2 Antibody Blocking Peptide - LS-E6776 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAP2 Antibody Blocking Peptide - LS-E15856 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

BRAP-AntibodyN-term-Blocking-peptide - BP19664a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human BRCA1-associated protein(BRAP) - CSB-EP773793HU CSB-BP773793HU CSB-MP773793HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human BRCA1-associated protein(BRAP) - CSB-YP773793HU from Cusabio Category Protein Source Yeast Species Human

BRAP / RNF52 (N-term HIS tag) - TP760349 from Acris Antibodies Category Protein Prices $199.00 Sizes 50 µg Source E. coli Species Human

Human BRAP protein - orb246867 from Biorbyt Category Protein Prices $366.00, $595.00, $986.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

BRAP-Antibody-Center-Blocking-peptide - BP5470c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

BRAP Recombinant Protein (OPCA03043) - OPCA03043 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Homo sapiens BRCA1-associated protein - AP73093 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

BRCA1-associated, Recombinant Protein - MBS1284886 from MyBioSource Category Protein Prices $190.00, $460.00, $750.00, $1,180.00, $1,395.00, $1,610.00, $1,610.00, $2,325.00, $2,770.00, $2,770.00 Sizes 50 µg (E-Coli), 200 µg (E-Coli), 500 µg (E-Coli), 1 mg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell

BRCA1-associated, Recombinant Protein - MBS9422789 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Recombinant Human BRAP Protein (1-592 aa), His-tagged - BRAP-1687H from Creative Biomart Category Protein Source Yeast Species Human

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