BRAP

Gene Symbol BRAP
Entrez Gene 8315
Alt Symbol BRAP2, IMP, RNF52
Species Human
Gene Type protein-coding
Description BRCA1 associated protein
Other Description BRCA1-associated protein|RING finger protein 52|galectin-2-binding protein|impedes mitogenic signal propagation|renal carcinoma antigen NY-REN-63
Swissprots O43238 B4DRM1 O75341 Q7Z569 B9EGS8
Accessions EAW97972 Q7Z569 AB208878 BAD92115 AF035620 AAC24200 AF035950 AAB88538 AK290379 BAF83068 AK299326 BAG61333 AK308279 AY332222 AAP93638 BC136698 AAI36699 BC136699 AAI36700 BU674276 DB460078 XM_005253944 XP_005254001 XM_011538788 XP_011537090 XM_011538789 XP_011537091 NM_006768 NP_006759
Function Negatively regulates MAP kinase activation by limiting the formation of Raf/MEK complexes probably by inactivation of the KSR1 scaffold protein. Also acts as a Ras responsive E3 ubiquitin ligase that, on activation of Ras, is modified by auto- polyubiquitination resulting in the release of inhibition of Raf/MEK complex formation. May also act as a cytoplasmic retention protein with a role in regulating nuclear transport. {ECO:0000269|PubMed:14724641, ECO:0000303|PubMed:10777491}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:9497340}.
Tissue Specificity Expressed in breast epithelial cell lines. {ECO:0000269|PubMed:9497340}.

BRAP CRISPR/Cas9 KO Plasmid (h) - sc-403847 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP HDR Plasmid (h) - sc-403847-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP Double Nickase Plasmid (h) - sc-403847-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP Double Nickase Plasmid (h2) - sc-403847-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP CRISPR Activation Plasmid (h) - sc-403847-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP CRISPR Activation Plasmid (h2) - sc-403847-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP Lentiviral Activation Particles (h) - sc-403847-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP Lentiviral Activation Particles (h2) - sc-403847-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

BRAP siRNA (h) - sc-95995 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRAP shRNA Plasmid (h) - sc-95995-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

BRAP shRNA (h) Lentiviral Particles - sc-95995-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU020871 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4045 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4045 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

BRAP siRNA (Human) - CRH5439 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

BRAP RNAi - H00008315-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

BRAP - MBS8210698 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human BRAP (NM_006768.3) - SHH247534 from Creative biogene

Category siRNA
Species Reactivities Human

BRAP shRNA Plasmid (Human) - CHH5439 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human
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