Gene Symbol | GBA |
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Entrez Gene | 2629 |
Alt Symbol | GBA1, GCB, GLUC |
Species | Human |
Gene Type | protein-coding |
Description | glucosidase, beta, acid |
Other Description | D-glucosyl-N-acylsphingosine glucohydrolase|acid beta-glucosidase|alglucerase|beta-GC|beta-glucocerebrosidase|glucosylceramidase|glucosylceramidase-like protein|imiglucerase|lysosomal glucocerebrosidase |
Swissprots | Q16545 B7Z6S1 J3KQK9 A8K796 Q9UMJ8 J3KQG4 Q4VX22 Q6I9R6 B7Z5G2 P04062 |
Accessions | AAA35874 AAA35875 AAA35876 AAA35878 AAA35879 AAC51820 AAC63056 EAW53100 EAW53101 EAW53102 EAW53103 P04062 AK291911 BAF84600 AK298900 BAH12898 AK300186 BAH13232 AK300829 BAH13357 AK300876 BAH13365 AK301374 BAH13467 AK301879 BAH13574 AK302000 BAH13605 AK311242 AK312502 BAG35404 AL547558 AU122729 AU131071 AU140959 AU141794 BC003356 AAH03356 BI458641 BX382279 BX477204 BX648487 D13286 BAA02545 DC297079 K02920 AAA35877 KJ690771 AID60277 KJ690772 AID60278 KJ690773 AID60279 M16328 AAA35873 M19285 AAA35880 M22212 XM_006711270 XP_006711333 XM_006726211 XP_006726274 XM_011509407 XP_011507709 XM_011546930 XP_011545232 NM_000157 NP_000148 NM_001005741 NP_001005741 NM_001005742 NP_001005742 NM_001171811 NP_001165282 NM_001171812 NP_001165283 NM_001005749 NM_001005750 |
Subcellular Location | Lysosome membrane {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Peripheral membrane protein {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Lumenal side {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2. |
Top Pathways | Lysosome, Sphingolipid metabolism, Other glycan degradation |
GBA 293T Cell Transient Overexpression Lysate(Denatured) - H00002629-T01 from Acris Antibodies
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GBA HEK293 Cell Transient Overexpression Lysate (Non-Denatured) - L100T6 from Acris Antibodies
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GBA overexpression lysate - LY433165 from Acris Antibodies
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GBA 293 Cell Lysate - 400149 from ABBIOTEC
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GBA 293 Cell Lysate - 409971 from ABBIOTEC
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Glucosylceramidase/GBA Overexpression Lysate (Denatured) - H00002629-T01 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBL1-10989 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-08846 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-09097 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBL1-10990 from Novus Biologicals
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β-glucosidase (h): 293T Lysate - sc-110483 from Santa Cruz Biotechnology
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GBA Over-expression Lysate Product - GWB-AF3F4D from Genway Biotech
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GBA Over-expression Lysate Product - GWB-AD8D92 from Genway Biotech
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Glucosylceramidase/GBA Overexpression Lysate (Denatured) - H00002629-T04 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-08850 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-08849 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-09099 from Novus Biologicals
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Glucosylceramidase/GBA Overexpression Lysate (Native) - NBP2-09098 from Novus Biologicals
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GBA-knockout Cell lysate - LC810416 from Acris Antibodies
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Panoply™ Human GBA Knockdown Stable Cell Line - CSC-DC006135 from Creative biogene
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Human GBA Knockout Cell Line-HeLa - CSC-RT0578 from Creative biogene
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GBA KO Cell Lysate-HeLa - CLKO-0083 from Creative biogene
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