GBA

Gene Symbol	GBA
Entrez Gene	2629
Alt Symbol	GBA1, GCB, GLUC
Species	Human
Gene Type	protein-coding
Description	glucosidase, beta, acid
Other Description	D-glucosyl-N-acylsphingosine glucohydrolase|acid beta-glucosidase|alglucerase|beta-GC|beta-glucocerebrosidase|glucosylceramidase|glucosylceramidase-like protein|imiglucerase|lysosomal glucocerebrosidase
Swissprots	Q16545 B7Z6S1 J3KQK9 A8K796 Q9UMJ8 J3KQG4 Q4VX22 Q6I9R6 B7Z5G2 P04062
Accessions	AAA35874 AAA35875 AAA35876 AAA35878 AAA35879 AAC51820 AAC63056 EAW53100 EAW53101 EAW53102 EAW53103 P04062 AK291911 BAF84600 AK298900 BAH12898 AK300186 BAH13232 AK300829 BAH13357 AK300876 BAH13365 AK301374 BAH13467 AK301879 BAH13574 AK302000 BAH13605 AK311242 AK312502 BAG35404 AL547558 AU122729 AU131071 AU140959 AU141794 BC003356 AAH03356 BI458641 BX382279 BX477204 BX648487 D13286 BAA02545 DC297079 K02920 AAA35877 KJ690771 AID60277 KJ690772 AID60278 KJ690773 AID60279 M16328 AAA35873 M19285 AAA35880 M22212 XM_006711270 XP_006711333 XM_006726211 XP_006726274 XM_011509407 XP_011507709 XM_011546930 XP_011545232 NM_000157 NP_000148 NM_001005741 NP_001005741 NM_001005742 NP_001005742 NM_001171811 NP_001165282 NM_001171812 NP_001165283 NM_001005749 NM_001005750
Subcellular Location	Lysosome membrane {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Peripheral membrane protein {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Lumenal side {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2.
Top Pathways	Lysosome, Sphingolipid metabolism, Other glycan degradation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human GBA full length protein - ab114257 from Abcam Category Protein Source Wheat germ Species Human

Human GBA peptide - ab104289 from Abcam Category Peptide

Human GBA protein fragment - ab112290 from Abcam Category Protein Source Wheat germ Species Human

Human GBA protein fragment - ab114258 from Abcam Category Protein Source Wheat germ Species Human

GBA / Glucosidase Beta Acid Antibody Blocking Peptide - LS-E22429 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

GBA / Glucosidase Beta Acid Antibody Blocking Peptide - LS-E9861 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Glucosylceramidase/GBA Partial Recombinant Protein - H00002629-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Glucosylceramidase/GBA Partial Recombinant Protein - H00002629-Q02 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Glucosylceramidase/GBA Recombinant Protein - H00002629-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

GC-Antibody-Center-Blocking-peptide - BP8937c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Recombinant Human Glucosylceramidase/GBA, CF - 7410-GH-010 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Met1-Gln536, with C-terminal 6-His tag

GBA Blocking Peptide - 33R-10317 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human Glucosidase Beta, Acid Protein - abx066804 from Abbexa Category Protein Source E.coli Species Human

Human Glucosidase Beta, Acid Protein - abx066805 from Abbexa Category Protein Source E.coli Species Human

Glucosylceramidase - H00002629-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glucosylceramidase - H00002629-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Glucosylceramidase - H00002629-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Glucosylceramidase - H00002629-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Glucosylceramidase - H00002629-Q02 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

Glucosylceramidase - H00002629-Q02-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

Glucosylceramidase - H00002629-Q02-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

Glucosidase Beta, Acid (GbA), Human - 20-8510 from ARP American Research Products Category Protein Prices $529.00 Sizes 50 µg Source E.coli Species Human

Glucosidase Beta, Acid (GbA), Human - 20-8511 from ARP American Research Products Category Protein Prices $529.00 Sizes 50 µg Source E.coli Species Human

Recombinant Human GBA - GBA-28982TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human GBA - GBA-28984TH from Creative Biomart Category Protein Source Wheat germ

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