GBA

Gene Symbol GBA
Entrez Gene 2629
Alt Symbol GBA1, GCB, GLUC
Species Human
Gene Type protein-coding
Description glucosidase, beta, acid
Other Description D-glucosyl-N-acylsphingosine glucohydrolase|acid beta-glucosidase|alglucerase|beta-GC|beta-glucocerebrosidase|glucosylceramidase|glucosylceramidase-like protein|imiglucerase|lysosomal glucocerebrosidase
Swissprots Q16545 B7Z6S1 J3KQK9 A8K796 Q9UMJ8 J3KQG4 Q4VX22 Q6I9R6 B7Z5G2 P04062
Accessions AAA35874 AAA35875 AAA35876 AAA35878 AAA35879 AAC51820 AAC63056 EAW53100 EAW53101 EAW53102 EAW53103 P04062 AK291911 BAF84600 AK298900 BAH12898 AK300186 BAH13232 AK300829 BAH13357 AK300876 BAH13365 AK301374 BAH13467 AK301879 BAH13574 AK302000 BAH13605 AK311242 AK312502 BAG35404 AL547558 AU122729 AU131071 AU140959 AU141794 BC003356 AAH03356 BI458641 BX382279 BX477204 BX648487 D13286 BAA02545 DC297079 K02920 AAA35877 KJ690771 AID60277 KJ690772 AID60278 KJ690773 AID60279 M16328 AAA35873 M19285 AAA35880 M22212 XM_006711270 XP_006711333 XM_006726211 XP_006726274 XM_011509407 XP_011507709 XM_011546930 XP_011545232 NM_000157 NP_000148 NM_001005741 NP_001005741 NM_001005742 NP_001005742 NM_001171811 NP_001165282 NM_001171812 NP_001165283 NM_001005749 NM_001005750
Subcellular Location Lysosome membrane {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Peripheral membrane protein {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}; Lumenal side {ECO:0000269|PubMed:17187079, ECO:0000269|PubMed:17897319, ECO:0000269|PubMed:18022370}. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2.
Top Pathways Lysosome, Sphingolipid metabolism, Other glycan degradation

β-glucosidase siRNA (h) - sc-44904 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β-glucosidase shRNA Plasmid (h) - sc-44904-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

β-glucosidase shRNA (h) Lentiviral Particles - sc-44904-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

Glucosylceramidase/GBA RNAi - H00002629-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Glucosylceramidase/GBA RNAi - H00002629-R03 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Glucosylceramidase/GBA RNAi - H00002629-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Glucosylceramidase/GBA RNAi - H00002629-R04 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

Glucosylceramidase/GBA RNAi - H00002629-R05 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU109121 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN9161 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9161 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

GBA siRNA (Human) - CRH1745 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBA - MBS8240173 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

Human GBA siRNA - orb262247 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

GBA shRNA Plasmid (Human) - CHH1745 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GBA miRNA 3'UTR clone - MiUTR3H-08473 from Creative biogene

Species Reactivities Human

GBA miRNA 3'UTR clone - MiUTR3H-08474 from Creative biogene

Species Reactivities Human

GBA miRNA 3'UTR clone - MiUTR3H-08475 from Creative biogene

Species Reactivities Human
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