CELF4

Gene Symbol CELF4
Entrez Gene 56853
Alt Symbol BRUNOL-4, BRUNOL4
Species Human
Gene Type protein-coding
Description CUGBP, Elav-like family member 4
Other Description Bruno -like 4, RNA binding protein|CELF-4|CUG-BP and ETR-3 like factor 4|CUG-BP- and ETR-3-like factor 4|CUGBP Elav-like family member 4|LYST-interacting protein LIP9|RNA-binding protein BRUNOL-4|RNA-binding protein BRUNOL4|bruno-like 4, RNA binding protein|bruno-like protein 4
Swissprots Q8N2M6 Q59EN7 Q9BZC1 Q9BQ96 Q86XB9 Q9NR84 Q9NR85
Accessions EAX01394 EAX01395 EAX01396 EAX01397 Q9BZC1 AA669357 AB209774 BAD93011 AF141345 AAG49448 AF248650 AAF86232 AF248651 AAF86233 AF329265 AAK07475 AK074596 BAC11082 AK091694 AK126716 AK295009 BAG58069 BC001946 AAH01946 BC004167 AAH04167 BC045711 AAH45711 BC127795 AAI27796 BF592968 BM671360 BM718619 BQ637723 XM_005258308 XP_005258365 XM_011526079 XP_011524381 XM_011526080 XP_011524382 XM_011526081 XP_011524383 XM_011526082 XP_011524384 XM_011526083 XP_011524385 XM_011526084 XP_011524386 XM_011526085 XP_011524387 XM_011526086 XP_011524388 XM_011526087 XP_011524389 XM_011526088 XP_011524390 XM_011526089 XP_011524391 XM_011526090 XP_011524392 XM_011526091 XP_011524393 XM_011526092 XP_011524394 XM_011526093 XP_011524395 XM_011526094 XP_011524396 XM_011526095 XP_011524397 XM_011526096 XP_011524398 XM_011526097 XP_011524399 XR_935233 NM_001025087 NP_001020258 NM_001025088 NP_001020259 NM_001025089 NP_001020260 NM_020180 NP_064565
Function RNA-binding protein implicated in the regulation of pre- mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA. {ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:12649496, ECO:0000269|PubMed:14973222, ECO:0000269|PubMed:15009664, ECO:0000269|PubMed:15894795}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14973222}. Cytoplasm {ECO:0000269|PubMed:14973222}.
Tissue Specificity Ubiquitous. Strongly expressed in the cerebellum, hippocampus, amygdala, temporal and frontal cortex and frontal lobes. {ECO:0000269|PubMed:11158314, ECO:0000269|PubMed:12438720, ECO:0000269|PubMed:16862542}.

BRUNOL4 (C-4) - sc-398292 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
BRUNOL4 (C-4): sc-398292. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

BRUNOL4 (G-19) - sc-84712 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
BRUNOL4 (G-19): sc-84712. Western blot analysis of BRUNOL4 expression in WI 38 whole cell lysate.

BRUNOL4 (H-50) - sc-367722 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

BRUNOL4 (S-15) - sc-84714 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
BRUNOL4 (S-15): sc-84714. Western blot analysis of BRUNOL4 expression in WI 38 whole cell lysate.

Anti-BRUNOL4 antibody - ab154710 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-BRUNOL4 antibody (ab154710) at 1/3000 dilutionLane 1 : H1299 whole cell lysateLane 2 : HCT116 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-BRUNOL4 antibody - ab94645 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-BRUNOL4 antibody (ab94645) at 1 µg/ml (in 5% skim milk / PBS buffer) + OVCAR3 cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-BRUNOL4 antibody - ab69698 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-BRUNOL4 antibody (ab69698) at 1/500 dilutionLane 1 : BRUNOL4 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/2500 dilution

Anti-BRUNOL4 antibody [EPR11824] - ab171740 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR11824
Flow cytometric analysis of permeabilized Hela cells labeling BRUNOL4 using ab171740 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

Anti-BRUNOL4 / CELF4 Antibody - LS-C155654 from LifeSpan Bioscience

Prices $245.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BRUNOL4 / CELF4 Antibody - LS-C306575 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-BRUNOL4 / CELF4 Antibody - LS-C309632 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BRUNOL4 / CELF4 Antibody - LS-C309636 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-BRUNOL4 / CELF4 Antibody (aa287-336) - LS-C110588 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CELF4 / BRUNOL4 antibody LS-C110588 Western blot of OVCAR-3 cell lysate.

BRUNOL4 Antibody - NBP1-89932 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BRUNOL4 Antibody - NBP2-15622 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BRUNOL4 Antibody [NBP2-15622] - Sample (30 ug of whole cell lysate) A: H1299 B: HCT116 7. 5% SDS PAGE gel, diluted at 1:3000.

BRUNOL4 Antibody - H00056853-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

BRUNOL4 Antibody - NBP1-57320 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: BRUNOL4 Antibody [NBP1-57320] - OVCAR-3 cell lysate, concentration 0.2-1 ug/ml.

BRUNOL4 Antibody - H00056853-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: BRUNOL4 Antibody [H00056853-D01P] - Analysis of BRUNOL4 expression in transfected 293T cell line by BRUNOL4 polyclonal antibody.Lane 1: BRUNOL4 transfected lysate(51.80 KDa).Lane 2: Non-transfected lysate.

BRUNOL4 Antibody - H00056853-D01 from Novus Biologicals

Prices $399.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-BRUNOL4 antibody produced in mouse - SAB1407749 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-BRUNOL4: <B>Cat. No. SAB1407749</B>: Antibody concentration: 10 μg/mL using HeLa cell.

Anti-BRUNOL4 antibody produced in rabbit - SAB1411114 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BRUNOL4: <B>Cat. No. SAB1411114</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~51.8 kDa using BRUNOL4 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-CELF4 antibody produced in rabbit - HPA037986 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CELF4: <B>Cat. No. HPA037986</B>: Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in neuronal cells.

Anti-BRUNOL4 antibody produced in rabbit - SAB2104564 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-BRUNOL4, antibody produced in rabbit: <B>Cat. No. SAB2104564</B>: Immunoblotting analysis of BRUNOL4 in OVCAR-3 cell lysate with BRUNOL4 anitbody at 1 μg/mL.

BRUNOL4 antibody - middle region (ARP40940_P050) - ARP40940_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

BRUNOL4 antibody - GTX121390 from GeneTex

Prices $119.00
Sizes 25 μl
Host Rabbit
Clonality Polyclonal
Anti-BRUNOL4 antibody used in IHC (Formalin-fixed paraffin-embedded sections). GTX121390
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