MCM4

Gene Symbol MCM4
Entrez Gene 4173
Alt Symbol CDC21, CDC54, NKCD, NKGCD, P1-CDC21, hCdc21
Species Human
Gene Type protein-coding
Description minichromosome maintenance complex component 4
Other Description CDC21 homolog|DNA replication licensing factor MCM4|homolog of S. pombe cell devision cycle 21|minichromosome maintenance deficient 4
Swissprots Q8NEH1 P33991 Q99658
Accessions AAB51723 AAC52018 AAS83108 CBX85473 EAW86684 EAW86685 EAW86686 P33991 AK022899 BAG51132 AK296913 BAG59468 AK309812 AM493756 CAM35476 BC031061 AAH31061 BF793151 BM781972 BQ058022 BQ689703 X74794 CAA52801 XM_005251234 XP_005251291 NM_005914 NP_005905 NM_182746 NP_877423
Function Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. {ECO:0000269|PubMed:9305914}.
Subcellular Location Nucleus {ECO:0000250}.
Top Pathways DNA replication, Cell cycle

MCM4 (D3H6N) XP ® Rabbit mAb - 12973 from Cell Signaling Technology

Prices $277.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D3H6N
Western blot analysis of extracts from various cell lines using MCM4 (D3H6N) XP ® Rabbit mAb.

MCM4 Antibody - 3228 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from various cell lines using MCM4 Antibody.

MCM4 (C-10) - sc-48407 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MCM4 (C-10): sc-48407. Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.

MCM4 (G-7) - sc-28317 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MCM4 (G-7): sc-28317. Immunoperoxidase staining of formalin fixed, paraffin-embedded human skin tissue showing nuclear staining of epidermal cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

MCM4 (C-20) - sc-9840 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCM4 (H-300) - sc-22779 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MCM4 (H-300): sc-22779. Immuno?fluorescence staining of methanol-fixed HeLa cells showing nuclear local?ization.

MCM4 (K-18) - sc-9841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MCM4 (phospho S54) antibody - ab74014 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MCM4 (phospho S54) antibody (ab74014) at 1/500 dilutionLane 1 : Extracts from COS-7 cells treated with nocodazole (1uM, 16hours)Lane 2 : Extracts from COS-7 cells treated with nocodazole (1uM, 16hours) with immunising phosphopeptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-MCM4 antibody - ab154315 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-MCM4 antibody (ab154315) at 1/5000 dilution + MOLT4 cell lysate at 30 µg

Anti-MCM4 antibody - ab88546 from Abcam

Prices $384.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
ab88546 at 10ug/ml staining MCM4 by immunofluorescence on HeLa cells.

Anti-MCM4 antibody - ab3728 from Abcam

Prices $378.00
Sizes 50 µl
Host Goat
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human ovarian carcinoma tissue labelling MCM4 with ab3728 at 1/1000 (1µg/ml). Detection: DAB.

Anti-MCM4 antibody - ab74237 from Abcam

Prices $378.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab74237 at 1/50 dilution staining MCM4 in human testis by Immunohistochemistry using Paraffin-embedded tissue, in the absence or presence of the immunising peptide.

Anti-MCM4 antibody - ab84153 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human lung small cell carcinoma tissue using 1/250 ab84153 followed by DAB staining.

Anti-MCM4 antibody - ab84152 from Abcam

Prices $376.00
Sizes 100 µl
Host Goat
Clonality Polyclonal
ab84152, at a dilution of 1/250, staining MCM4 in formalin fixed, paraffin embedded human seminoma by Immunohistochemistry. Detection: by DAB staining.

Anti-MCM4 antibody [EPR5245] - ab124836 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR5245
All lanes : Anti-MCM4 antibody [EPR5245] (ab124836) at 1/50000 dilutionLane 1 : HeLa cell lysateLane 2 : Molt-4 cell lysateLane 3 : A431 cell lysateLysates/proteins at 10 µg per lane.

Anti-MCM4 antibody [EPR5247(2)] - ab188578 from Abcam

Host Rabbit
Clonality Monoclonal
Clone EPR5247(2)
All lanes : Anti-MCM4 antibody [EPR5247(2)] (ab188578) at 1/5000 dilutionLane 1 : 293 cell lysateLane 2 : Jurkat cell lysateLane 3 : K562 cell lysateLane 4 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat anti-rabbit IgG, (H+L), peroxidase conjugate at 1/1000 dilution

Anti-MCM4 Antibody - LS-C72290 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MCM4 Antibody (aa411-460) - LS-C31745 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-MCM4 Antibody (aa97-146) - LS-C31744 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-MCM4 Antibody (N-Terminus) - LS-C125924 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-MCM4 Antibody (C-Terminus) - LS-C31746 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-MCM4 Antibody (aa636-665, AP) - LS-C226865 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCM4 Antibody (aa636-665, APC) - LS-C226866 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCM4 Antibody (aa636-665, Biotin) - LS-C226867 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCM4 Antibody (aa636-665, FITC) - LS-C226868 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Search more