Gene Symbol | PSME2 |
---|---|
Entrez Gene | 5721 |
Alt Symbol | PA28B, PA28beta, REGbeta |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
Other Description | 11S regulator complex beta subunit|11S regulator complex subunit beta|MCP activator, 31-kD subunit|REG-beta|activator of multicatalytic protease subunit 2|cell migration-inducing protein 22|proteasome activator 28 subunit beta|proteasome activator 28-beta|proteasome activator complex subunit 2|proteasome activator hPA28 subunit beta |
Swissprots | Q15129 Q9UL46 |
Accessions | AAF02218 EAW66100 EAW66101 Q9UL46 AK026580 AK225876 AK311569 AY771595 AAX11425 BC004368 AAH04368 BC019885 AAH19885 BC072025 AAH72025 BX161498 CAD61943 CR541657 CAG46458 CR541743 CAG46543 D45248 BAA08205 DQ893404 ABM84330 DQ896722 ABM87721 XM_006720213 XP_006720276 NM_002818 NP_002809 |
Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
Top Pathways | Proteasome, Antigen processing and presentation |