Gene Symbol | PSME2 |
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Entrez Gene | 5721 |
Alt Symbol | PA28B, PA28beta, REGbeta |
Species | Human |
Gene Type | protein-coding |
Description | proteasome (prosome, macropain) activator subunit 2 (PA28 beta) |
Other Description | 11S regulator complex beta subunit|11S regulator complex subunit beta|MCP activator, 31-kD subunit|REG-beta|activator of multicatalytic protease subunit 2|cell migration-inducing protein 22|proteasome activator 28 subunit beta|proteasome activator 28-beta|proteasome activator complex subunit 2|proteasome activator hPA28 subunit beta |
Swissprots | Q15129 Q9UL46 |
Accessions | AAF02218 EAW66100 EAW66101 Q9UL46 AK026580 AK225876 AK311569 AY771595 AAX11425 BC004368 AAH04368 BC019885 AAH19885 BC072025 AAH72025 BX161498 CAD61943 CR541657 CAG46458 CR541743 CAG46543 D45248 BAA08205 DQ893404 ABM84330 DQ896722 ABM87721 XM_006720213 XP_006720276 NM_002818 NP_002809 |
Function | Implicated in immunoproteasome assembly and required for efficient antigen processing. The PA28 activator complex enhances the generation of class I binding peptides by altering the cleavage pattern of the proteasome. |
Top Pathways | Proteasome, Antigen processing and presentation |
PA28β siRNA (h) - sc-40798 from Santa Cruz Biotechnology
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PA28β shRNA Plasmid (h) - sc-40798-SH from Santa Cruz Biotechnology
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PA28β shRNA (h) Lentiviral Particles - sc-40798-V from Santa Cruz Biotechnology
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PA28 Activator beta Subunit/PSME2 RNAi - H00005721-R01 from Novus Biologicals
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MISSION® esiRNA - EHU115781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN17629 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17629 from Sigma-Aldrich
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PSME2 siRNA (Human) - CRH3866 from Cohesion Biosciences
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shRNA set against Human PSME2(NM_002818.2) - SHR148836 from Creative biogene
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Human PSME2 siRNA - orb264368 from Biorbyt
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PSME2 shRNA Plasmid (Human) - CHH3866 from Cohesion Biosciences
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PSME2 miRNA 3'UTR clone - MiUTR1H-08395 from Creative biogene
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