LAT2

Gene Symbol	LAT2
Entrez Gene	7462
Alt Symbol	HSPC046, LAB, NTAL, WBSCR15, WBSCR5, WSCR5
Species	Human
Gene Type	protein-coding
Description	linker for activation of T cells family, member 2
Other Description	Williams-Beuren syndrome chromosomal region 15 protein|Williams-Beuren syndrome chromosomal region 5 protein|linker for activation of B-cells|linker for activation of T cells, transmembrane adaptor 2|linker for activation of T-cells family member 2|membrane-associated adapter molecule|non-T-cell activation linker
Swissprots	D3DXF9 A8K4F1 Q9BXX8 A6NFK6 A8K209 Q9NZY9 Q9GZY6
Accessions	AAF74978 AAS07404 AAS07405 CAC33299 CAE90041 EAW69609 EAW69610 EAW69611 EAW69612 EAW69613 EAW69614 Q9GZY6 AF086239 AF161531 AAF29018 AF252611 AAK37429 AF252612 AAK37430 AF252613 AAK37633 AF252614 AAK37431 AF257135 AAF91352 AI492348 AK002099 BAA92084 AK092904 BAG52627 AK225150 AK290074 BAF82763 AK290916 BAF83605 AY190023 AAO63155 BC001609 AAH01609 BC006080 BC009204 AAH09204 BM468969 EU832618 ACE87709 EU832690 ACE87022 XM_011516558 XP_011514860 NM_014146 NP_054865 NM_032463 NP_115852 NM_032464 NP_115853
Function	Involved in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. May also be involved in BCR (B-cell antigen receptor)-mediated signaling in B-cells and FCGR1 (high affinity immunoglobulin gamma Fc receptor I)-mediated signaling in myeloid cells. Couples activation of these receptors and their associated kinases with distal intracellular events through the recruitment of GRB2. {ECO:0000269|PubMed:12486104, ECO:0000269|PubMed:12514734, ECO:0000269|PubMed:15010370}.
Subcellular Location	Cell membrane {ECO:0000269|PubMed:12486104, ECO:0000269|PubMed:12514734}; Single-pass type III membrane protein {ECO:0000269|PubMed:12486104, ECO:0000269|PubMed:12514734}. Note=Present in lipid rafts.
Tissue Specificity	Highly expressed in spleen, peripheral blood lymphocytes, and germinal centers of lymph nodes. Also expressed in placenta, lung, pancreas and small intestine. Present in B- cells, NK cells and monocytes. Absent from T-cells (at protein level). {ECO:0000269|PubMed:11124535, ECO:0000269|PubMed:12486104, ECO:0000269|PubMed:12514734, ECO:0000269|PubMed:16160011}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

LAT2-Over-expression-Lysate - LY14424a from Abgent, a WuXi AppTec company Category Cell Lysate Prices $325.00 Sizes 100 µg

LAT2 overexpression lysate - LY410097 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LAT2 overexpression lysate - LY410098 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LAT2 overexpression lysate - LY415475 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LAT2 overexpression lysate - LY429810 from Acris Antibodies Category Cell Lysate Prices $280.00 Sizes 100 µg

LAT2 293 Cell Lysate - 405203 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

LAT2 293 Cell Lysate - 407290 from ABBIOTEC Category Cell Lysate Prices $392.00 Sizes 100 µg

NTAL Overexpression Lysate (Native) - NBL1-12447 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NTAL Overexpression Lysate (Native) - NBL1-12446 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NTAL Overexpression Lysate (Native) - NBP2-06018 from Novus Biologicals Category Cell Lysate Prices $329.00 Sizes 100 µg

NTAL (h): 293T Lysate - sc-177644 from Santa Cruz Biotechnology Category Cell Lysate Prices $205.00 Sizes 100 µg/200 µl Species Human

LAT2 Over-expression Lysate Product - GWB-85CDB0 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

LAT2 Over-expression Lysate Product - GWB-359AE4 from Genway Biotech Category Cell Lysate Prices $346.00 Sizes 100 µg Species Human

Panoply™ Human LAT2 Knockdown Stable Cell Line - CSC-DC008559 from Creative biogene Category Cell Line Species Human

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