Gene Symbol | CACTIN |
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Entrez Gene | 58509 |
Alt Symbol | C19orf29, NY-REN-24, fSAPc |
Species | Human |
Gene Type | protein-coding |
Description | cactin, spliceosome C complex subunit |
Other Description | NY REN 24 antigen|cactin|functional spliceosome-associated protein c|renal carcinoma antigen NY-REN-24 |
Swissprots | Q9BTA6 A6NNA9 Q9Y5A4 A9UL12 Q7LE08 O75229 Q8WUQ7 |
Accessions | AAC24305 AAC32903 Q8WUQ7 AF052087 AF155102 AAD42868 AK299963 BAG61789 AW027691 AY917150 AAX84551 BC004262 AAH04262 BC019848 AAH19848 BC156484 AAI56485 BC172549 AAI72549 BF196424 CF272634 CN305928 CO248922 XM_011528160 XP_011526462 XM_011528161 XP_011526463 NM_001080543 NP_001074012 NM_021231 NP_067054 |
Function | Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing. {ECO:0000269|PubMed:20829348}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:20829348}. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus. |
Cactin (D-16) - sc-240077 from Santa Cruz Biotechnology
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Cactin (K-14) - sc-240078 from Santa Cruz Biotechnology
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Anti-Cactin antibody - ab109803 from Abcam
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Anti-FSAPc / C19orf29 Antibody (aa460-510) - LS-C148804 from LifeSpan Bioscience
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Anti-FSAPc / C19orf29 Antibody (aa475-525) - LS-C290035 from LifeSpan Bioscience
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Anti-FSAPc / C19orf29 Antibody (aa75-125) - LS-C290033 from LifeSpan Bioscience
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Cactin Antibody - NBP1-70775 from Novus Biologicals
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Cactin Antibody - NBP1-86678 from Novus Biologicals
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Cactin Antibody - NBP1-86679 from Novus Biologicals
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Cactin Antibody - NBP1-78746 from Novus Biologicals
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Cactin Antibody - NBP1-78747 from Novus Biologicals
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C19orf29 Polyclonal Antibody - bs-9960R from Bioss
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Anti-C19orf29 antibody produced in rabbit - HPA042504 from Sigma-Aldrich
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Anti-C19orf29 antibody produced in rabbit - HPA042548 from Sigma-Aldrich
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Cactin Antibody - A303-349A from Bethyl Labs
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Cactin Antibody - A303-350A from Bethyl Labs
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Cactin Antibody AbVantage™ Pack - A311-236A from Bethyl Labs
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CACTIN Polyclonal Antibody - PA5-23500 from Thermo Fisher Scientific
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Anti-FSAPc / C19orf29 Antibody (aa320-521) - LS-C358163 from LifeSpan Bioscience
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C19orf29 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-9960R-A350 from Bioss
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C19orf29 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-9960R-A488 from Bioss
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C19orf29 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-9960R-A555 from Bioss
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C19orf29 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-9960R-A647 from Bioss
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C19orf29 Polyclonal Antibody, Cy3 Conjugated - bs-9960R-Cy3 from Bioss
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C19orf29 Polyclonal Antibody, Cy5 Conjugated - bs-9960R-Cy5 from Bioss
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