| Gene Symbol |
CACTIN
|
| Entrez Gene |
58509
|
| Alt Symbol |
C19orf29, NY-REN-24, fSAPc
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
cactin, spliceosome C complex subunit
|
| Other Description |
NY REN 24 antigen|cactin|functional spliceosome-associated protein c|renal carcinoma antigen NY-REN-24
|
| Swissprots |
Q9BTA6 A6NNA9 Q9Y5A4 A9UL12 Q7LE08 O75229 Q8WUQ7
|
| Accessions |
AAC24305 AAC32903 Q8WUQ7 AF052087 AF155102 AAD42868 AK299963 BAG61789 AW027691 AY917150 AAX84551 BC004262 AAH04262 BC019848 AAH19848 BC156484 AAI56485 BC172549 AAI72549 BF196424 CF272634 CN305928 CO248922 XM_011528160 XP_011526462 XM_011528161 XP_011526463 NM_001080543 NP_001074012 NM_021231 NP_067054
|
| Function |
Involved in the regulation of innate immune response. Acts as negative regulator of Toll-like receptor and interferon- regulatory factor (IRF) signaling pathways. Contributes to the regulation of transcriptional activation of NF-kappa-B target genes in response to endogenous proinflammatory stimuli. May play a role during early embryonic development. Probably involved in pre-mRNA splicing. {ECO:0000269|PubMed:20829348}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:20829348}. Note=Nuclear localization with a speckled expression pattern in some cells. Colocalizes with NFKBIL1 in the nucleus.
|
![Western Blot: Cactin Overexpression Lysate (Native) [NBP2-08404] - Cactin Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C19orf29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/14783_Cactin-Overexpression-Lysate-%2528Native%2529-Western-Blot-NBP2-08404-img0002.jpg)
![Western Blot: Cactin Overexpression Lysate (Native) [NBP2-06542] - Cactin Overexpression Lysate (Native) Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for C19orf29.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/6028_Cactin-Overexpression-Lysate-(Native)-Western-Blot-NBP2-06542-img0002.jpg)