HS3ST3B1

Gene Symbol HS3ST3B1
Entrez Gene 9953
Alt Symbol 3-OST-3B, 3OST3B1, h3-OST-3B
Species Human
Gene Type protein-coding
Description heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
Other Description heparan sulfate 3-O-sulfotransferase 3B1|heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1|heparan sulfate glucosamine 3-O-sulfotransferase 3B1
Swissprots D3DTS6 Q9Y662 B3KN58
Accessions EAW89953 EAW89954 Q9Y662 AF105377 AAD30209 AK023723 BAG51220 BC063301 AAH63301 BC069664 AAH69664 BC069725 AAH69725 BM968044 DA388077 XR_934130 NM_006041 NP_006032 NR_130138
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N- unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non- anticoagulant heparan sulfate to anticoagulant heparan sulfate. {ECO:0000269|PubMed:10520990}.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Ubiquitous. Most abundant in liver and placenta, followed by heart and kidney. {ECO:0000269|PubMed:9988767}.
Top Pathways Glycosaminoglycan biosynthesis - heparan sulfate / heparin

HS3ST3B1 CRISPR/Cas9 KO Plasmid (h) - sc-409765 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 HDR Plasmid (h) - sc-409765-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 Double Nickase Plasmid (h) - sc-409765-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 Double Nickase Plasmid (h2) - sc-409765-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 CRISPR Activation Plasmid (h) - sc-409765-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 CRISPR Activation Plasmid (h2) - sc-409765-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 Lentiviral Activation Particles (h) - sc-409765-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 Lentiviral Activation Particles (h2) - sc-409765-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

HS3ST3B1 siRNA (h) - sc-93963 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HS3ST3B1 shRNA Plasmid (h) - sc-93963-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

HS3ST3B1 shRNA (h) Lentiviral Particles - sc-93963-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU113761 from Sigma-Aldrich

Category siRNA

CompoZr® Knockout ZFN Kit - CKOZFN10309 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10309 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05169 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05169

HS3ST3B1 siRNA (Human) - CRH6693 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

HS3ST3B1 - MBS8240014 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human HS3ST3B1 (NM_006041.1) - SHH314993 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human HS3ST3B1(NM_006041.1) - SHH131753 from Creative biogene

Category siRNA
Species Reactivities Human

HS3ST3B1 shRNA Plasmid (Human) - CHH6693 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

HS3ST3B1 miRNA 3'UTR clone - MiUTR1H-04704 from Creative biogene

Species Reactivities Human
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