| Gene Symbol |
OXER1
|
| Entrez Gene |
165140
|
| Alt Symbol |
GPCR, GPR170, TG1019
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
oxoeicosanoid (OXE) receptor 1
|
| Other Description |
5-oxo-ETE G-protein coupled receptor|5-oxo-ETE acid G-protein-coupled receptor 1|G-protein coupled receptor 170|G-protein coupled receptor R527|G-protein coupled receptor TG1019|oxoeicosanoid receptor 1
|
| Swissprots |
Q8NGW4 Q86WP7 Q8TDS5
|
| Accessions |
AAY14700 BAB89343 BAC05878 EAX00312 Q8TDS5 AB083055 BAC11806 AY158687 AAO17739 BC063549 AAH63549 NM_148962 NP_683765
|
| Function |
Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}.
|