Gene Symbol | OXER1 |
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Entrez Gene | 165140 |
Alt Symbol | GPCR, GPR170, TG1019 |
Species | Human |
Gene Type | protein-coding |
Description | oxoeicosanoid (OXE) receptor 1 |
Other Description | 5-oxo-ETE G-protein coupled receptor|5-oxo-ETE acid G-protein-coupled receptor 1|G-protein coupled receptor 170|G-protein coupled receptor R527|G-protein coupled receptor TG1019|oxoeicosanoid receptor 1 |
Swissprots | Q8NGW4 Q86WP7 Q8TDS5 |
Accessions | AAY14700 BAB89343 BAC05878 EAX00312 Q8TDS5 AB083055 BAC11806 AY158687 AAO17739 BC063549 AAH63549 NM_148962 NP_683765 |
Function | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}. |
TG1019 CRISPR/Cas9 KO Plasmid (h) - sc-409060 from Santa Cruz Biotechnology
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TG1019 HDR Plasmid (h) - sc-409060-HDR from Santa Cruz Biotechnology
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TG1019 Double Nickase Plasmid (h) - sc-409060-NIC from Santa Cruz Biotechnology
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TG1019 Double Nickase Plasmid (h2) - sc-409060-NIC-2 from Santa Cruz Biotechnology
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TG1019 CRISPR Activation Plasmid (h) - sc-409060-ACT from Santa Cruz Biotechnology
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TG1019 CRISPR Activation Plasmid (h2) - sc-409060-ACT-2 from Santa Cruz Biotechnology
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TG1019 Lentiviral Activation Particles (h) - sc-409060-LAC from Santa Cruz Biotechnology
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TG1019 Lentiviral Activation Particles (h2) - sc-409060-LAC-2 from Santa Cruz Biotechnology
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TG1019 siRNA (h) - sc-61677 from Santa Cruz Biotechnology
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TG1019 shRNA Plasmid (h) - sc-61677-SH from Santa Cruz Biotechnology
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TG1019 shRNA (h) Lentiviral Particles - sc-61677-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU142961 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16216 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16216 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR03856 from Sigma-Aldrich
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OXER1 siRNA (Human) - CRJ6024 from Cohesion Biosciences
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OXER1/5-oxo-ETE GPCR RNAi - H00165140-R02 from Novus Biologicals
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shRNA set against Human OXER1 (NM_148962.4) - SHH369336 from Creative biogene
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Human OXER1 siRNA - orb276525 from Biorbyt
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OXER1 shRNA Plasmid (Human) - CHJ6024 from Cohesion Biosciences
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OXER1 miRNA 3'UTR clone - MiUTR1H-07427 from Creative biogene
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