Gene Symbol | OXER1 |
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Entrez Gene | 165140 |
Alt Symbol | GPCR, GPR170, TG1019 |
Species | Human |
Gene Type | protein-coding |
Description | oxoeicosanoid (OXE) receptor 1 |
Other Description | 5-oxo-ETE G-protein coupled receptor|5-oxo-ETE acid G-protein-coupled receptor 1|G-protein coupled receptor 170|G-protein coupled receptor R527|G-protein coupled receptor TG1019|oxoeicosanoid receptor 1 |
Swissprots | Q8NGW4 Q86WP7 Q8TDS5 |
Accessions | AAY14700 BAB89343 BAC05878 EAX00312 Q8TDS5 AB083055 BAC11806 AY158687 AAO17739 BC063549 AAH63549 NM_148962 NP_683765 |
Function | Receptor for eicosanoids and polyunsaturated fatty acids such as 5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OXO-ETE), 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic acid (5(S)-HPETE) and arachidonic acid. Seems to be coupled to the G(i)/G(o), families of heteromeric G proteins. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in various tissues except brain. Expression is more intense in liver, kidney, peripheral leukocyte, lung, and spleen than in other tissues. Highly expressed in eosinophils, neutrophils, and lung macrophages. {ECO:0000269|PubMed:12065583, ECO:0000269|PubMed:12606753}. |
Human 5-oxo-ETE GPCR full length protein - ab165776 from Abcam
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Human 5-oxo-ETE GPCR peptide - ab23083 from Abcam
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OXER1 Antibody Blocking Peptide - LS-E27675 from LifeSpan Bioscience
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OXER1 Antibody Blocking Peptide - LS-E28529 from LifeSpan Bioscience
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OXER1 Antibody Blocking Peptide - LS-E28530 from LifeSpan Bioscience
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OXER1 Antibody Blocking Peptide - LS-E28531 from LifeSpan Bioscience
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Recombinant Human OXER1/5-oxo-ETE GPCR Protein - H00165140-P01 from Novus Biologicals
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Recombinant Human OXER1/5-oxo-ETE GPCR Protein - H00165140-G01 from Novus Biologicals
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OXER1 Immunizing peptide - orb66181 from Biorbyt
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5-oxo-ETE GPCR Peptide - AC21-2491-P from Abcore
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Oxoeicosanoid receptor 1 - H00165140-G01 from Acris Antibodies
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Oxoeicosanoid receptor 1 - H00165140-P01 from Acris Antibodies
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OXER1 Peptide - 42-849P from ProSci
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TG1019 (R251) Peptide - BS3237P from Bioworld Technology
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OXER1, Peptide - MBS427417 from MyBioSource
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GPR170 Blocking Peptide - abx061966 from Abbexa
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OXER1 Peptide, Human - M34GP11188H from Creative Peptides
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GPR170 Blocking Peptide - CBP7356 from Cohesion Biosciences
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OXER1/5-oxo-ETE GPCR Recombinant Protein Antigen - NBP2-49006PEP from Novus Biologicals
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Oxoeicosanoid receptor 1 (OXER1), Recombinant Protein - MBS7025252 from MyBioSource
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GPR170 peptide - orb339573 from Biorbyt
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