LRRFIP1

Gene Symbol	LRRFIP1
Entrez Gene	9208
Alt Symbol	FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP
Species	Human
Gene Type	protein-coding
Description	leucine rich repeat (in FLII) interacting protein 1
Other Description	GC-binding factor 2|LRR FLII-interacting protein 1|NEDD8-conjugating enzyme|TAR RNA-interacting protein|leucine-rich repeat flightless-interacting protein 1
Swissprots	Q32MZ5 O75766 Q6PKG2 Q53T49 E9PGZ2 Q9Y607 Q32MZ4 O75799
Accessions	AAY14672 AAY14673 EAW71122 EAW71123 EAW71124 EAW71125 Q32MZ4 AA975133 AF115510 AAD41258 AJ223075 CAA11076 AK000884 AK298270 BAG60532 AK307485 BC001385 AAH01385 BC004958 BC010662 AAH10662 BC018883 BC019335 AAH19335 BC071618 BC083492 BC108913 AAI08914 BC108914 AAI08915 BE390005 BG699031 BU685896 EU831431 ACE87118 EU831523 ACE86442 EU832771 ACE87782 EU832772 ACE87783 GQ129315 ACT64449 GQ129316 ACT64450 U69609 AAC32037 XM_005246112 XP_005246169 XM_005246115 XP_005246172 XM_005246116 XP_005246173 XM_005246118 XP_005246175 XM_005246119 XP_005246176 XM_005246120 XP_005246177 XM_005246121 XP_005246178 XM_005246122 XP_005246179 XM_005246124 XP_005246181 XM_005246125 XP_005246182 XM_005246126 XP_005246183 XM_005246128 XP_005246185 XM_005246129 XP_005246186 XM_005246130 XP_005246187 XM_005246131 XP_005246188 XM_005246132 XP_005246189 XM_005246133 XP_005246190 XM_005246134 XP_005246191 XM_005246135 XP_005246192 XM_005246136 XP_005246193 XM_005246141 XP_005246198 XM_005246142 XP_005246199 XM_006712842 XP_006712905 XM_006712843 XP_006712906 XM_006712844 XP_006712907 XM_006712845 XP_006712908 XM_006712846 XP_006712909 XM_006712847 XP_006712910 XM_006712848 XP_006712911 XM_011512152 XP_011510454 XM_011512153 XP_011510455 XM_011512154 XP_011510456 XM_011512155 XP_011510457 XM_011512156 XP_011510458 XM_011512157 XP_011510459 XM_011512158 XP_011510460 XM_011512159 XP_011510461 XM_011512160 XP_011510462 XM_011512161 XP_011510463 XM_011512162 XP_011510464 XM_011512163 XP_011510465 XM_011512164 XP_011510466 XM_011512165 XP_011510467 XM_011512166 XP_011510468 XR_923063 NM_001137550 NP_001131022 NM_001137551 NP_001131023 NM_001137552 NP_001131024 NM_001137553 NP_001131025 NM_004735 NP_004726
Function	Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. {ECO:0000269|PubMed:10364563, ECO:0000269|PubMed:14522076, ECO:0000269|PubMed:16199883, ECO:0000269|PubMed:19265123, ECO:0000269|PubMed:9705290}.
Subcellular Location	Nucleus. Cytoplasm.
Tissue Specificity	Ubiquitously expressed. {ECO:0000269|PubMed:9671805, ECO:0000269|PubMed:9705290}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human LRRFIP1 full length protein - ab152961 from Abcam Category Protein Source Wheat germ Species Human

Human LRRFIP1 protein fragment - ab152962 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human LRRFIP1 Protein - H00009208-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human LRRFIP1 Protein - H00009208-P01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

LRRFIP1 Blocking Peptide - NBP1-76545PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

Human LRRFIP1 protein - orb244356 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

Human LRRFIP1 Protein - abx067755 from Abbexa Category Protein Source E.coli Species Human

Human LRRFIP1 Protein - abx067754 from Abbexa Category Protein Source E.coli Species Human

LRRFIP1 - H00009208-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

LRRFIP1 - H00009208-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

LRRFIP1 - H00009208-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

LRRFIP1 - H00009208-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

LRRFIP1 control peptide - AP26112CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Leucine Rich Repeat In FLII Interacting Protein 1 - 20-9300 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

Leucine Rich Repeat In FLII Interacting Protein 1 - 20-9301 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

LRRFIP1 Peptide - 6219P from ProSci Category Peptide Species Human

LRRFIP1 fusion protein - Ag2673 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human LRRFIP1, GST-tagged - LRRFIP1-646H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) - RPH718Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) - RPH718Hu02 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) - RPH718Hu01 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant Leucine Rich Repeat In FLII Interacting Protein 1 (LRRFIP1) - RPH718Hu02 from Cloud-clone Category Protein Source E.coli Species Human

Recombinant human Leucine-rich repeat flightless-interacting protein 1 - CSB-YP013175HU(B) CSB-BP013175HU(B) CSB-MP013175HU(B) from Cusabio Category Protein Source Yeast or Baculovirus or Mammalian cell Species Human

Recombinant human Leucine-rich repeat flightless-interacting protein 1 - CSB-EP013175HU(B) from Cusabio Category Protein Source E.coli Species Human

Recombinant Human Leucine-rich repeat flightless-interacting protein 1(LRRFIP1) - CSB-YP654886HU CSB-EP654886HU CSB-BP654886HU CSB-MP654886HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

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