LRRFIP1

Gene Symbol LRRFIP1
Entrez Gene 9208
Alt Symbol FLAP-1, FLAP1, FLIIAP1, GCF-2, GCF2, HUFI-1, TRIP
Species Human
Gene Type protein-coding
Description leucine rich repeat (in FLII) interacting protein 1
Other Description GC-binding factor 2|LRR FLII-interacting protein 1|NEDD8-conjugating enzyme|TAR RNA-interacting protein|leucine-rich repeat flightless-interacting protein 1
Swissprots Q32MZ5 O75766 Q6PKG2 Q53T49 E9PGZ2 Q9Y607 Q32MZ4 O75799
Accessions AAY14672 AAY14673 EAW71122 EAW71123 EAW71124 EAW71125 Q32MZ4 AA975133 AF115510 AAD41258 AJ223075 CAA11076 AK000884 AK298270 BAG60532 AK307485 BC001385 AAH01385 BC004958 BC010662 AAH10662 BC018883 BC019335 AAH19335 BC071618 BC083492 BC108913 AAI08914 BC108914 AAI08915 BE390005 BG699031 BU685896 EU831431 ACE87118 EU831523 ACE86442 EU832771 ACE87782 EU832772 ACE87783 GQ129315 ACT64449 GQ129316 ACT64450 U69609 AAC32037 XM_005246112 XP_005246169 XM_005246115 XP_005246172 XM_005246116 XP_005246173 XM_005246118 XP_005246175 XM_005246119 XP_005246176 XM_005246120 XP_005246177 XM_005246121 XP_005246178 XM_005246122 XP_005246179 XM_005246124 XP_005246181 XM_005246125 XP_005246182 XM_005246126 XP_005246183 XM_005246128 XP_005246185 XM_005246129 XP_005246186 XM_005246130 XP_005246187 XM_005246131 XP_005246188 XM_005246132 XP_005246189 XM_005246133 XP_005246190 XM_005246134 XP_005246191 XM_005246135 XP_005246192 XM_005246136 XP_005246193 XM_005246141 XP_005246198 XM_005246142 XP_005246199 XM_006712842 XP_006712905 XM_006712843 XP_006712906 XM_006712844 XP_006712907 XM_006712845 XP_006712908 XM_006712846 XP_006712909 XM_006712847 XP_006712910 XM_006712848 XP_006712911 XM_011512152 XP_011510454 XM_011512153 XP_011510455 XM_011512154 XP_011510456 XM_011512155 XP_011510457 XM_011512156 XP_011510458 XM_011512157 XP_011510459 XM_011512158 XP_011510460 XM_011512159 XP_011510461 XM_011512160 XP_011510462 XM_011512161 XP_011510463 XM_011512162 XP_011510464 XM_011512163 XP_011510465 XM_011512164 XP_011510466 XM_011512165 XP_011510467 XM_011512166 XP_011510468 XR_923063 NM_001137550 NP_001131022 NM_001137551 NP_001131023 NM_001137552 NP_001131024 NM_001137553 NP_001131025 NM_004735 NP_004726
Function Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding. {ECO:0000269|PubMed:10364563, ECO:0000269|PubMed:14522076, ECO:0000269|PubMed:16199883, ECO:0000269|PubMed:19265123, ECO:0000269|PubMed:9705290}.
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Ubiquitously expressed. {ECO:0000269|PubMed:9671805, ECO:0000269|PubMed:9705290}.

LRRFIP1 CRISPR/Cas9 KO Plasmid (h) - sc-405090 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 HDR Plasmid (h) - sc-405090-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 Double Nickase Plasmid (h) - sc-405090-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 Double Nickase Plasmid (h2) - sc-405090-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 CRISPR Activation Plasmid (h) - sc-405090-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 CRISPR Activation Plasmid (h2) - sc-405090-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 Lentiviral Activation Particles (h) - sc-405090-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 Lentiviral Activation Particles (h2) - sc-405090-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LRRFIP1 siRNA (h2) - sc-270288 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRFIP1 shRNA Plasmid (h2) - sc-270288-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRFIP1 shRNA (h2) Lentiviral Particles - sc-270288-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LRRFIP1 RNAi - H00009208-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU099251 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN12770 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12770 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

LRRFIP1 siRNA (Human) - CRH6093 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human LRRFIP1 (NM_004735.3) - SHH334935 from Creative biogene

Category siRNA
Species Reactivities Human

LRRFIP1 shRNA Plasmid (Human) - CHH6093 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

LRRFIP1 miRNA 3'UTR clone - MiUTR3H-05818 from Creative biogene

Species Reactivities Human

LRRFIP1 miRNA 3'UTR clone - MiUTR3H-05819 from Creative biogene

Species Reactivities Human

LRRFIP1 miRNA 3'UTR clone - MiUTR3H-05820 from Creative biogene

Species Reactivities Human
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