| Gene Symbol |
KIF23
|
| Entrez Gene |
9493
|
| Alt Symbol |
CHO1, KNSL5, MKLP-1, MKLP1
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
kinesin family member 23
|
| Other Description |
kinesin-like 5 (mitotic kinesin-like protein 1)|kinesin-like protein KIF23
|
| Swissprots |
Q8WVP0 B4E1K0 Q02241
|
| Accessions |
EAW77841 EAW77842 Q02241 AA291944 AI131325 AK303874 BAG64812 AK308322 AK308361 AK310402 AU133373 BC017705 AAH17705 BC051826 AAH51826 BG939827 BI093060 BX327654 BX477359 DB445953 DR000298 EU176620 ABW03421 X67155 CAA47628 XM_005254796 XP_005254853 XM_005254797 XP_005254854 XM_005254798 XP_005254855 XM_005254799 XP_005254856 XM_011522238 XP_011520540 XM_011522239 XP_011520541 XM_011522240 XP_011520542 NM_001281301 NP_001268230 NM_004856 NP_004847 NM_138555 NP_612565
|
| Function |
Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. {ECO:0000269|PubMed:16103226, ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:22522702}.
|
| Subcellular Location |
Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
|
| Top Pathways |
MicroRNAs in cancer
|