KIF23

Gene Symbol KIF23
Entrez Gene 9493
Alt Symbol CHO1, KNSL5, MKLP-1, MKLP1
Species Human
Gene Type protein-coding
Description kinesin family member 23
Other Description kinesin-like 5 (mitotic kinesin-like protein 1)|kinesin-like protein KIF23
Swissprots Q8WVP0 B4E1K0 Q02241
Accessions EAW77841 EAW77842 Q02241 AA291944 AI131325 AK303874 BAG64812 AK308322 AK308361 AK310402 AU133373 BC017705 AAH17705 BC051826 AAH51826 BG939827 BI093060 BX327654 BX477359 DB445953 DR000298 EU176620 ABW03421 X67155 CAA47628 XM_005254796 XP_005254853 XM_005254797 XP_005254854 XM_005254798 XP_005254855 XM_005254799 XP_005254856 XM_011522238 XP_011520540 XM_011522239 XP_011520541 XM_011522240 XP_011520542 NM_001281301 NP_001268230 NM_004856 NP_004847 NM_138555 NP_612565
Function Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Essential for cytokinesis in Rho-mediated signaling. Required for the localization of ECT2 to the central spindle. Plus-end-directed motor enzyme that moves antiparallel microtubules in vitro. {ECO:0000269|PubMed:16103226, ECO:0000269|PubMed:16236794, ECO:0000269|PubMed:22522702}.
Subcellular Location Nucleus. Cytoplasm, cytoskeleton, spindle. Midbody. Note=Localizes to the interzone of mitotic spindles. Detected at the midbody during later stages of mitotic cytokinesis.
Top Pathways MicroRNAs in cancer

MKLP-1 (C-12) - sc-390113 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKLP-1 (C-12): sc-390113. Western blot analysis of MKLP-1 expression in K-562 (A), HeLa (B) and Jurkat (C) whole cell lysates.

MKLP-1 (N-19) - sc-867 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MKLP-1 (N-19): sc-867. Western blot analysis of MKLP-1 expression in K-562 whole cell lysate.

MKLP-1 (Q-16) - sc-33336 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKLP-1 (Q-16): sc-33336. Western blot analysis of MKLP-1 expression in non-transfected: sc-117752 (A) and human MKLP-1 transfected: sc-116361 (B) 293T whole cell lysates.

MKLP-1 (H-110) - sc-22793 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MKLP-1 (H-110): sc-22793. Immunoperoxidase staining of formalin fixed, paraffin-embedded human pancreas tissue showing cytoplasmic staining of glandular cells.

MKLP-1 (24) - sc-136473 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MKLP-1 (24): sc-136473. Western blot analysis of MKLP-1 expression in K-562 whole cell lysate.

MKLP-1 (D-17) - sc-33335 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
MKLP-1 (D-17): sc-33335. Western blot analysis of MKLP-1 expression in non-transfected: sc-117752 (A) and human MKLP-1 transfected: sc-113424 (B) 293T whole cell lyastes.

Anti-MKLP1 antibody - ab9259 from Abcam

Prices $379.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab9259 stained HeLa cells. The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab9259, 5µg/ml) overnight at +4°C. The secondary antibody (green) was ab96899, DyLight® 488 goat anti-rabbit IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-MKLP1 antibody - ab168964 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-MKLP1 antibody (ab168964) at 1 µg/mlLane 1 : MKLP1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.

Anti-MKLP1 antibody (Agarose) - ab1293 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-MKLP1 antibody [EPR10879] - ab174304 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR10879
Anti-MKLP1 antibody [EPR10879] (ab174304) at 1/5000 dilution (purified) + RAW264.7 cell lysate at 20 µgSecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-KIF23 / MKLP1 Antibody (aa32-81) IHC-plus™ - LS-B1543 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-KIF23 / MKLP1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B1543 concentration 5 ug/ml.

Anti-KIF23 / MKLP1 Antibody (Agarose) - LS-C72731 from LifeSpan Bioscience

Prices $635.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KIF23 / MKLP1 Antibody - LS-C72730 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KIF23 / MKLP1 Antibody (aa1-50, Agarose) - LS-C291101 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-KIF23 / MKLP1 Antibody (N-Terminus) - LS-C31743 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Jurkat Cell Lysate

Anti-KIF23 / MKLP1 Antibody (aa647-696) - LS-C109844 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIF23 / MKLP1 antibody LS-C109844 Western blot of NCI-H226 cell lysate.

Anti-KIF23 / MKLP1 Antibody (aa539-588) - LS-C109848 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
KIF23 / MKLP1 antibody LS-C109848 Western blot of COLO205 cell lysate.

Anti-KIF23 / MKLP1 Antibody (aa1-50) - LS-C285976 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human MKLP1 by Western Blot. Samples: Whole cell lysate (10 ug/lane) from asynchronous (A) or mitotically-enriched (M) HeLa cells. Mitotically enriched HeLa cells were prepared by treatment with Nocodazole (500 ng/ml; 12h). Antibody: Affinity purified rabbit anti-MKLP1 antibody used at 1 ug/ml. Detection: Chemiluminescence with an exposure time of 2 minutes.

MKLP1 Antibody - NBP1-58126 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MKLP1 Antibody [NBP1-58126] - COLO205 cells lysate, concentration 0.2-1 ug/ml.

MKLP1 Antibody - NB100-211 from Novus Biologicals

Prices $369.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: MKLP1 Antibody [NB100-211] - Whole cell lysate (10 ug/lane) from asynchronous (A) or mitotically-enriched (M) HeLa cells. Mitotically enriched HeLa cells were prepared by treatment with Nocodazole (500 ng/ml; 12h). Antibody used at 1 ug/ml.

MKLP1 Antibody - H00009493-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

MKLP1 Antibody - NBP2-17299 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MKLP1 Antibody [NBP2-17299] - Sample (30 ug of whole cell lysate) A: HeLa 5% SDS PAGE gel, diluted at 1:2000.

MKLP1 Antibody [Agarose Immobilized] - NB600-422 from Novus Biologicals

Host Rabbit
Clonality Polyclonal

MKLP1 Polyclonal Antibody - bs-9315R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-KIF23 antibody produced in mouse - SAB1410009 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunofluorescence</B><BR/>Anti-KIF23: <B>Cat. No. SAB1410009</B>: Antibody concentration: 10 μg/mL using HeLa cell.
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