Gene Symbol | TMEM30B |
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Entrez Gene | 161291 |
Alt Symbol | CDC50B |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 30B |
Other Description | P4-ATPase flippase complex beta subunit TMEM30B|cell cycle control protein 50B |
Swissprots | Q3MIR4 Q14D00 B3KR84 |
Accessions | EAW80799 Q3MIR4 AK091169 BAG52296 AL080078 BC101726 AAI01727 BC113559 AAI13560 DA431345 DA666826 DB220251 DB237714 NM_001017970 NP_001017970 |
Function | Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. {ECO:0000269|PubMed:20961850, ECO:0000305}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:20961850}; Multi-pass membrane protein {ECO:0000269|PubMed:20961850}. |
TMEM30B Antibody Blocking Peptide - LS-E7669 from LifeSpan Bioscience
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TMEM30B Antibody Blocking Peptide - LS-E16429 from LifeSpan Bioscience
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CC50B-Antibody-N-term-Blocking-Peptide - BP4968a from Abgent, a WuXi AppTec company
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TMEM30B Blocking Peptide - 33R-9922 from Fitzgerald
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TMEM30B fusion protein - ag20199 from Proteintech Group
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TMEM30B fusion protein - ag20155 from Proteintech Group
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TMEM30B Recombinant Protein Antigen - NBP1-85718PEP from Novus Biologicals
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TMEM30B Peptide, Human - M34GP16225H from Creative Peptides
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Cell cycle control protein 50B (TMEM30B), Recombinant Protein - MBS7031817 from MyBioSource
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