Gene Symbol | TMEM30B |
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Entrez Gene | 161291 |
Alt Symbol | CDC50B |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protein 30B |
Other Description | P4-ATPase flippase complex beta subunit TMEM30B|cell cycle control protein 50B |
Swissprots | Q3MIR4 Q14D00 B3KR84 |
Accessions | EAW80799 Q3MIR4 AK091169 BAG52296 AL080078 BC101726 AAI01727 BC113559 AAI13560 DA431345 DA666826 DB220251 DB237714 NM_001017970 NP_001017970 |
Function | Accessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. The beta subunit may assist in binding of the phospholipid substrate (Probable). Can mediate the export of alpha subunits ATP8A1, ATP8B1, ATP8B2 and ATP8B4 from the ER to the plasma membrane. {ECO:0000269|PubMed:20961850, ECO:0000305}. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:20961850}; Multi-pass membrane protein {ECO:0000269|PubMed:20961850}. |
Cdc50B (S-15) - sc-164014 from Santa Cruz Biotechnology
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Cdc50B (Y-12) - sc-164015 from Santa Cruz Biotechnology
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Cdc50B (H-92) - sc-382072 from Santa Cruz Biotechnology
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Anti-TMEM30B antibody - ab104105 from Abcam
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Anti-TMEM30B antibody - ab83813 from Abcam
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Anti-TMEM30B antibody - ab137233 from Abcam
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Anti-TMEM30B antibody [EPR14409] - ab185944 from Abcam
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Anti-TMEM30B Antibody (aa42-71, AP) - LS-C233432 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71, Biotin) - LS-C233433 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71, APC) - LS-C233434 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71, FITC) - LS-C233435 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71, PE) - LS-C233440 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71, Azide-free, HRP) - LS-C249585 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa50-80) - LS-C320034 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa108-157) - LS-C102133 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa72-121) - LS-C200793 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa91-140) IHC-plus⢠- LS-B10009 from LifeSpan Bioscience
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Anti-TMEM30B Antibody (aa42-71) - LS-C168375 from LifeSpan Bioscience
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TMEM30B Antibody - NBP1-59534 from Novus Biologicals
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TMEM30B Antibody - NBP1-85718 from Novus Biologicals
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ANTI-CC50B (N-TERMINAL) antibody produced in rabbit - SAB1306496 from Sigma-Aldrich
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Anti-TMEM30B antibody produced in rabbit - HPA043162 from Sigma-Aldrich
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Anti-TMEM30B antibody produced in rabbit - SAB4500621 from Sigma-Aldrich
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TMEM30B antibody - middle region (ARP44716_P050) - ARP44716_P050 from Aviva Systems Biology
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CC50B Antibody - N-terminal region (OAAB02381) - OAAB02381 from Aviva Systems Biology
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