PPP1R14A

Gene Symbol PPP1R14A
Entrez Gene 94274
Alt Symbol CPI-17, CPI17, PPP1INL
Species Human
Gene Type protein-coding
Description protein phosphatase 1, regulatory (inhibitor) subunit 14A
Other Description 17 kDa PKC-potentiated inhibitory protein of PP1|17-KDa protein|17-kDa PKC-potentiated inhibitory protein of PP1|PKC-potentiated inhibitory protein of PP1|protein kinase C-potentiated inhibitor protein of 17 kDa|protein phosphatase 1 regulatory subunit 14A
Swissprots Q96A00 Q96S54 Q7Z4X7
Accessions AAL24445 EAW56764 EAW56765 Q96A00 AB056508 BAB62502 AB056509 BAB62503 AF123763 AAP97242 AY050670 AAL25828 BC021089 AAH21089 DQ892130 ABM83056 DQ895324 ABM86250 ES314242 NM_001243947 NP_001230876 NM_033256 NP_150281
Function Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.
Subcellular Location Cytoplasm {ECO:0000250}.
Tissue Specificity Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. {ECO:0000269|PubMed:11467857}.
Top Pathways Vascular smooth muscle contraction

CPI-17 (C-1) - sc-365841 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPI-17 (C-1): sc-365841. Western blot analysis of CPI-17 expression in non-transfected: sc-117752 (A) and human CPI-17 transfected: sc-175952 (B) 293T whole cell lysates.

CPI-17 (A-20) - sc-30927 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPI-17 (A-20): sc-30927. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

CPI-17 (A-7) - sc-28378 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPI-17 (A-7): sc-28378. Western blot analysis of HIS-tagged porcine recombinant CPI-17 proteins.

CPI-17 (F-4) - sc-48406 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
CPI-17 (F-4): sc-48406. Immunofluorescence staining of methanol-fixed HeLa cells showing membrane and cytoplasmic localization.

CPI-17 (H-60) - sc-25751 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
CPI-17 (H-60): sc-25751. Western blot analysis of human recombinant CPI-17 fusion protein.

CPI-17 (K-20) - sc-30930 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPI-17 (K-20): sc-30930. Immunoperoxidase staining of formalin fixed, paraffin-embedded human cerebral cortex tissue showing cytoplasmic staining of neuronal cells and glial cells.

CPI-17 (N-20) - sc-17561 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
CPI-17 (N-20): sc-17561. Western blot analysis of CPI-17 expression in non-transfected: sc-117752 (A) and mouse CPI-17 transfected: sc-126662 (B) 293T whole cell lysates.

p-CPI-17 (Thr 38) - sc-17560 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
p-CPI-17 (Thr 38)-R: sc-17560-R. Western blot analysis of CPI-17 phosphorylation in untreated (A) and lambda protein phosphatase (sc-200312A) treated (B) human platelet extracts.

Anti-CPI17 alpha (phospho T38) antibody - ab52174 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab52174 at 1/50 dilution staining CPI17a in human breast carcinoma by Immunohistochemistry, paraffin embedded tissue, in the presence (right image) and absence (left image) of the immunising peptide.

Anti-CPI17 alpha (phospho T38) antibody - ab195817 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CPI17 alpha (phospho T38) antibody (ab195817) at 1/500 dilutionLane 1 : RAW264.7 whole cell lysate with antigen-specific peptideLane 2 : RAW264.7 whole cell lysateLysates/proteins at 12.5 µg per lane.

Anti-CPI17 alpha antibody - ab131451 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of methanol fixed HeLa cells labelling CKI17 alpha with ab131451 antibody at a dilution of 1/100.

Anti-CPI17 alpha antibody - ab52170 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab52170 staining CPI17 alpha in human breast carcinoma by Immunohistochemsitry, paraffin embedded tissue, in the absence and presence of the immunising pepide.

Anti-CPI17 alpha antibody - ab177038 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-CPI17 alpha antibody (ab177038) at 1/500 dilution + A431 cell lysate

Anti-CPI17 alpha antibody - ab173375 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-CPI17 alpha antibody (ab173375) at 1 µg/mlLane 1 : CPI17 alpha-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/7500 dilutiondeveloped using the ECL technique

Anti-CPI17 alpha antibody - ab57698 from Abcam

Prices $376.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Western blot against tagged recombinant protein immunogen using ab57698 CPI17 alpha antibody at 1ug/ml.

Anti-CPI17 alpha antibody - ab196246 from Abcam

Prices $376.00
Sizes 250 µg
Host Rabbit
Clonality Polyclonal
Anti-CPI17 alpha antibody (ab196246) at 1/500 dilution + A431 cell lysate

Anti-CPI17 alpha antibody [E305] - ab32213 from Abcam

Prices $381.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E305
Lanes 1, 2 & 4 : purified at 1/1000 dilutionLane 3 : RAW264.7 purified at 1/1000 dilutionLane 1 : C6 cell lysateLane 2 : PC-12 cell lysateLane 3 : cell lysateLane 4 : NIH/3T3 cell lysateLysates/proteins at 10 µg per lane.SecondaryHRP goat anti-rabbit (H+L) at 1/1000 dilution

Anti-PPP1R14A / CPI-17 Antibody - LS-C14630 from LifeSpan Bioscience

Prices $530.00
Sizes 200 µg
Host Rabbit
Clonality Polyclonal

Anti-PPP1R14A / CPI-17 Antibody (aa7-56) - LS-C151580 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PPP1R14A / CPI-17 antibody Western Blot of PANC1.

Anti-PPP1R14A / CPI-17 Antibody (phospho-Thr38) - LS-C117328 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma, using CPI17 alpha (Phospho-Thr38) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-PPP1R14A / CPI-17 Antibody (aa5-54) - LS-C118085 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human breast carcinoma tissue, using CPI17 alpha (Ab-38) Antibody. The picture on the right is treated with the synthesized peptide.

Anti-PPP1R14A / CPI-17 Antibody (aa1-147, clone 4H10) - LS-C93787 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4H10
The Cell lysates of A549 (30 ug) were resolved by SDS-PAGE, transferred to NC membrane and probed with anti-human PPP1R14A (1:500). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Anti-PPP1R14A / CPI-17 Antibody (Lys32) - LS-C177687 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of CPI-17 (K32) pAb in paraffin-embedded human heart tissue.

Anti-PPP1R14A / CPI-17 Antibody (N-Terminus, clone E305) - LS-C49558 from LifeSpan Bioscience

Prices $480.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone E305
IHC of paraffin-embedded human normal aorta using anti-CPI- 17 alpha antibody.

Anti-PPP1R14A / CPI-17 Antibody (phospho-Thr38) - LS-C178046 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of p-CPI-17 (T38) pAb in paraffin-embedded human heart tissue.
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