| Gene Symbol | HIST1H2BL |
|---|---|
| Entrez Gene | 8340 |
| Alt Symbol | H2B/c, H2BFC, dJ97D16.4 |
| Species | Human |
| Gene Type | protein-coding |
| Description | histone cluster 1, H2bl |
| Other Description | H2B histone family, member C|histone 1, H2bl|histone H2B type 1-L|histone H2B.c |
| Swissprots | B2R5A3 Q99880 Q52LW9 |
| Accessions | AAN06695 CAB06035 EAX03106 Q99880 AK312114 BAG35050 BC093759 BC093761 EU446971 ABZ92500 NM_003519 NP_003510 |
| Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
| Subcellular Location | Nucleus. Chromosome. |
| Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
histone cluster 1, H2bl, ELISA Kit - MBS9316422 from MyBioSource
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Human HIST1H2BL ELISA Kit - E018766 from Biobool
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