Gene Symbol | HIST1H2BL |
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Entrez Gene | 8340 |
Alt Symbol | H2B/c, H2BFC, dJ97D16.4 |
Species | Human |
Gene Type | protein-coding |
Description | histone cluster 1, H2bl |
Other Description | H2B histone family, member C|histone 1, H2bl|histone H2B type 1-L|histone H2B.c |
Swissprots | B2R5A3 Q99880 Q52LW9 |
Accessions | AAN06695 CAB06035 EAX03106 Q99880 AK312114 BAG35050 BC093759 BC093761 EU446971 ABZ92500 NM_003519 NP_003510 |
Function | Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. |
Subcellular Location | Nucleus. Chromosome. |
Top Pathways | Systemic lupus erythematosus, Viral carcinogenesis, Alcoholism |
Histone cluster 1 H2BL CRISPR/Cas9 KO Plasmid (h) - sc-411143 from Santa Cruz Biotechnology
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Histone cluster 1 H2BL HDR Plasmid (h) - sc-411143-HDR from Santa Cruz Biotechnology
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Histone cluster 1 H2BL Double Nickase Plasmid (h) - sc-411143-NIC from Santa Cruz Biotechnology
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Histone cluster 1 H2BL Double Nickase Plasmid (h2) - sc-411143-NIC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BL CRISPR Activation Plasmid (h) - sc-411143-ACT from Santa Cruz Biotechnology
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Histone cluster 1 H2BL CRISPR Activation Plasmid (h2) - sc-411143-ACT-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BL Lentiviral Activation Particles (h) - sc-411143-LAC from Santa Cruz Biotechnology
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Histone cluster 1 H2BL Lentiviral Activation Particles (h2) - sc-411143-LAC-2 from Santa Cruz Biotechnology
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Histone cluster 1 H2BL siRNA (h) - sc-105482 from Santa Cruz Biotechnology
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Histone cluster 1 H2BL shRNA Plasmid (h) - sc-105482-SH from Santa Cruz Biotechnology
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Histone cluster 1 H2BL shRNA (h) Lentiviral Particles - sc-105482-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN10079 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10079 from Sigma-Aldrich
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HIST1H2BL siRNA (Human) - CRH5460 from Cohesion Biosciences
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HIST1H2BL RNAi - H00008340-R01 from Novus Biologicals
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HIST1H2BL - MBS8240373 from MyBioSource
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shRNA set against Human HIST1H2BL (NM_003519.3) - SHH312641 from Creative biogene
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shRNA set against Human HIST1H2BL(NM_003519.3) - SHH122591 from Creative biogene
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Human HIST1H2BL siRNA - orb265962 from Biorbyt
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HIST1H2BL shRNA Plasmid (Human) - CHH5460 from Cohesion Biosciences
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HIST1H2BL miRNA 3'UTR clone - MiUTR1H-04539 from Creative biogene
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