| Gene Symbol |
CLINT1
|
| Entrez Gene |
9685
|
| Alt Symbol |
CLINT, ENTH, EPN4, EPNR
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
clathrin interactor 1
|
| Other Description |
clathrin interacting protein localized in the trans-Golgi region|enthoprotin|epsin 4|epsin-related protein|epsinR
|
| Swissprots |
Q96E05 Q8NAF1 D3DQJ6 B7Z6F8 Q14677
|
| Accessions |
CCQ43453 EAW61585 EAW61586 EAW61587 EAW61588 Q14677 AF434813 AAL30768 AK092765 BAC03971 AK128594 AK300257 BAH13244 AL529948 AL833548 BC004467 AAH04467 BC013091 AAH13091 BC030264 BI461076 BK000414 DAA00062 BP246338 D79993 BAA11488 XM_011534701 XP_011533003 XM_011534702 XP_011533004 XM_011534703 XP_011533005 NM_001195555 NP_001182484 NM_001195556 NP_001182485 NM_014666 NP_055481
|
| Function |
Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. {ECO:0000269|PubMed:12429846, ECO:0000269|PubMed:12538641}.
|
| Subcellular Location |
Cytoplasm. Cytoplasm, perinuclear region. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, clathrin-coated vesicle. Note=Found throughout the cell, with the exception of the cell surface. Concentrated in the perinuclear region and associated with clathrin-coated vesicles close to the trans-Golgi network.
|
| Tissue Specificity |
Ubiquitously expressed at low to intermediate levels. {ECO:0000269|PubMed:12429846, ECO:0000269|PubMed:12538641}.
|