NUMA1

Gene Symbol NUMA1
Entrez Gene 4926
Alt Symbol NMP-22, NUMA
Species Human
Gene Type protein-coding
Description nuclear mitotic apparatus protein 1
Other Description SP-H antigen|centrophilin stabilizes mitotic spindle in mitotic cells|nuclear matrix protein-22|structural nuclear protein
Swissprots Q14981 Q14980 Q9BTE9 H0YH75
Accessions AAC33408 AAD16994 EAW74821 EAW74822 EAW74823 EAW74824 EAW74825 EAW74826 EAW74827 EAW74828 EAW74829 EAW74830 EAW74831 Q14980 AB208841 BAD92078 AB210007 BAE06089 AB621824 BAK64159 AK290509 BAF83198 AK307577 AK309041 BC004165 AAH04165 BC008345 AAH08345 BC013023 AAH13023 BC027493 AAH27493 BC032228 BC036808 BC043499 AAH43499 BC068539 BC103765 AAI03766 BG754891 BG771637 DQ586970 Z11583 CAA77669 Z11584 CAA77670 Z14227 Z14228 Z14229 XM_006718564 XP_006718627 XM_011545054 XP_011543356 XM_011545055 XP_011543357 XM_011545056 XP_011543358 XM_011545057 XP_011543359 XM_011545058 XP_011543360 XM_011545059 XP_011543361 XM_011545060 XP_011543362 XM_011545061 XP_011543363 XM_011545062 XP_011543364 XM_011545063 XP_011543365 XM_011545064 XP_011543366 XM_011545065 XP_011543367 XM_011545066 XP_011543368 NM_001286561 NP_001273490 NM_006185 NP_006176 NR_104476
Function Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions. {ECO:0000269|PubMed:19255246}.
Subcellular Location Isoform Numa-s: Cytoplasm. Note=Mainly clustered at the centrosomal region.

NuMA CRISPR/Cas9 KO Plasmid (h) - sc-401570 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA HDR Plasmid (h) - sc-401570-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA Double Nickase Plasmid (h) - sc-401570-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA Double Nickase Plasmid (h2) - sc-401570-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA CRISPR Activation Plasmid (h) - sc-401570-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA CRISPR Activation Plasmid (h2) - sc-401570-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA Lentiviral Activation Particles (h) - sc-401570-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA Lentiviral Activation Particles (h2) - sc-401570-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

NuMA siRNA (h) - sc-43978 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NuMA shRNA Plasmid (h) - sc-43978-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

NuMA shRNA (h) Lentiviral Particles - sc-43978-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU059141 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN15614 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15614 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR05776 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr05776

NUMA1 siRNA (Human) - CRH3276 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NuMA RNAi - H00004926-R01 from Novus Biologicals

Category siRNA
Prices $409.00
Sizes 20 nmol
Species Reactivities Human

shRNA set against Human NUMA1 (NM_006185.2) - SHH356304 from Creative biogene

Category siRNA
Species Reactivities Human

Human NUMA1 siRNA - orb263778 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

NUMA1 shRNA Plasmid (Human) - CHH3276 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

NUMA1 miRNA 3'UTR clone - MiUTR1H-06977 from Creative biogene

Species Reactivities Human
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