SLC4A1

Gene Symbol SLC4A1
Entrez Gene 6521
Alt Symbol AE1, BND3, CD233, DI, EMPB3, EPB3, FR, RTA1A, SW, WD, WD1, WR
Species Human
Gene Type protein-coding
Description solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
Other Description Diego blood group|Froese blood group|Swann blood group|Waldner blood group|Wright blood group|anion exchange protein 1|anion exchanger 1|anion exchanger-1|band 3 anion transport protein|erythrocyte membrane protein band 3|erythroid anion exchange protein|solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)|solute carrier family 4, anion exchanger, number 1
Swissprots G4V2I6 Q4KKW9 Q9UDJ1 Q9UCY7 Q1ZZ45 P02730 Q4VB84 P78487
Accessions AAA51670 AAA51671 AAY57324 ADN22950 ADN22951 ADN22952 ADN22953 ADN22954 ADN22955 EAW51614 P02730 AB526447 BAJ22989 AF113686 AM919470 CAP46016 BC096106 AAH96106 BC096107 AAH96107 BC099628 AAH99628 BC099629 AAH99629 BC101570 AAI01571 BC101574 AAI01575 DQ419529 ABD74692 GQ981383 ADN39420 GQ981384 ADN39421 GQ981385 ADN39422 GQ981386 ADN39423 GQ981387 ADN39424 M27819 AAA35514 S68680 AAC60608 X12609 CAA31128 XM_005257593 XP_005257650 XM_011525129 XP_011523431 XM_011525130 XP_011523432 XM_011525131 XP_011523433 NM_000342 NP_000333
Function Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. {ECO:0000269|PubMed:10926824, ECO:0000269|PubMed:14734552, ECO:0000269|PubMed:1538405, ECO:0000269|PubMed:20151848, ECO:0000269|PubMed:24121512}.
Subcellular Location Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney.
Tissue Specificity Detected in erythrocytes (at protein level). Erythrocytes. {ECO:0000269|PubMed:10926824, ECO:0000269|PubMed:1538405, ECO:0000269|PubMed:23219802}.
Top Pathways Collecting duct acid secretion

Band 3 anion transport protein (SLC4A1), Human, ELISA Kit - E01B0969 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7231969 from MyBioSource

Category ELISA Kit
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Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7250917 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7233795 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL.

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7210770 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7223337 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7245636 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7219808 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7201121 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7235171 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7230564 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 1.0 ng/mL

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7235687 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Band 3 anion transport protein (SLC4A1), ELISA Kit - MBS7215516 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human SLC4A1 ELISA Kit - E004441 from Biobool

Category ELISA Kit
Sensitivity 1.0 ng/mL.

Band 3 Anion Transport Protein (SLC4A1), ELISA Kit - MBS9906679 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
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