SLC4A1

Gene Symbol	SLC4A1
Entrez Gene	6521
Alt Symbol	AE1, BND3, CD233, DI, EMPB3, EPB3, FR, RTA1A, SW, WD, WD1, WR
Species	Human
Gene Type	protein-coding
Description	solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
Other Description	Diego blood group|Froese blood group|Swann blood group|Waldner blood group|Wright blood group|anion exchange protein 1|anion exchanger 1|anion exchanger-1|band 3 anion transport protein|erythrocyte membrane protein band 3|erythroid anion exchange protein|solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)|solute carrier family 4, anion exchanger, number 1
Swissprots	G4V2I6 Q4KKW9 Q9UDJ1 Q9UCY7 Q1ZZ45 P02730 Q4VB84 P78487
Accessions	AAA51670 AAA51671 AAY57324 ADN22950 ADN22951 ADN22952 ADN22953 ADN22954 ADN22955 EAW51614 P02730 AB526447 BAJ22989 AF113686 AM919470 CAP46016 BC096106 AAH96106 BC096107 AAH96107 BC099628 AAH99628 BC099629 AAH99629 BC101570 AAI01571 BC101574 AAI01575 DQ419529 ABD74692 GQ981383 ADN39420 GQ981384 ADN39421 GQ981385 ADN39422 GQ981386 ADN39423 GQ981387 ADN39424 M27819 AAA35514 S68680 AAC60608 X12609 CAA31128 XM_005257593 XP_005257650 XM_011525129 XP_011523431 XM_011525130 XP_011523432 XM_011525131 XP_011523433 NM_000342 NP_000333
Function	Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride-bicarbonate exchange in the kidney, and is required for normal acidification of the urine. {ECO:0000269|PubMed:10926824, ECO:0000269|PubMed:14734552, ECO:0000269|PubMed:1538405, ECO:0000269|PubMed:20151848, ECO:0000269|PubMed:24121512}.
Subcellular Location	Cell membrane; Multi-pass membrane protein. Basolateral cell membrane; Multi-pass membrane protein. Note=Detected in the erythrocyte cell membrane and on the basolateral membrane of alpha-intercalated cells in the collecting duct in the kidney.
Tissue Specificity	Detected in erythrocytes (at protein level). Erythrocytes. {ECO:0000269|PubMed:10926824, ECO:0000269|PubMed:1538405, ECO:0000269|PubMed:23219802}.
Top Pathways	Collecting duct acid secretion

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Band 3 peptide - ab177142 from Abcam Category Peptide

Human Band 3 protein fragment - ab114402 from Abcam Category Protein Prices $420.00 Sizes 10 µg Source Wheat germ Species Human

SLC4A1 / Band 3 / AE1 Antibody Blocking Peptide - LS-E11955 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human Band 3 Protein - H00006521-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human Band 3 Protein - H00006521-G01 from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Source Wheat Germ Species Human

SLC4A1-Antibody-N-term-Blocking-Peptide - BP14828a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

SLC4A1 Blocking Peptide - 33R-7368 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Human AE1 Protein - abx065356 from Abbexa Category Protein Source E.coli Species Human

CD233 / SLC4A1 - H00006521-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD233 / SLC4A1 - H00006521-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

CD233 / SLC4A1 - H00006521-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

SLC4A1 fusion protein - ag13076 from Proteintech Group Category Protein Source E. coli-derived, PKG Species Human

Recombinant Human SLC4A1 - SLC4A1-26065TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Anion Exchange Protein 1 (AE1) - RPB681Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Anion Exchange Protein 1 (AE1) - RPB681Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

Recombinant Anion Exchange Protein 1 (AE1) - RPB681Hu01 from Cloud-clone Category Protein Source E.coli Species Human

CD233 / SLC4A1 - TP318312 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Band 3 Protein, Peptide - MBS659540 from MyBioSource Category Protein Prices $625.00 Sizes 25 mg Source Synthetic peptide Species Human

Band 3 Protein, Peptide - MBS659066 from MyBioSource Category Protein Prices $625.00 Sizes 25 mg Source Synthetic peptide Species Human

Band 3 Recombinant Protein Antigen - NBP1-90226PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

Band 3 Recombinant Protein Antigen - NBP2-49409PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E. coli Species Human

SLC4A1 Peptide, Human - M34GP14594H from Creative Peptides Category Peptide Source Synthetic. Species Human

SLC4A1 Recombinant Protein (OPCD01158) - OPCD01158 from Aviva Systems Biology Category Protein Source E.coli Species Human

Recombinant Human Band 3 anion transport protein (SLC4A1),Partial - CSB-EP021663HUb1 from Cusabio Category Protein Source E.coli Species Human

Band 3 anion transport protein (SLC4A1), Recombinant Protein - MBS965008 from MyBioSource Category Protein Prices $1,650.00, $1,805.00, $1,945.00, $2,055.00, $2,255.00, $2,305.00, $2,565.00, $2,855.00, $3,255.00, $4,060.00 Sizes 50 µg (Baculovirus), 500 µg (E-Coli), 500 µg (Yeast), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 1 mg (Yeast), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Search more