AP2S1

Gene Symbol AP2S1
Entrez Gene 1175
Alt Symbol AP17, CLAPS2, FBH3, FBHOk, HHC3
Species Human
Gene Type protein-coding
Description adaptor-related protein complex 2, sigma 1 subunit
Other Description AP-2 complex subunit sigma|HA2 17 kDa subunit|adaptor protein complex AP-2 subunit sigma|clathrin assembly protein 2 sigma small chain|clathrin coat assembly protein AP17|clathrin coat-associated protein AP17|clathrin-associated/assembly/adaptor protein, small 2 (17kD)|plasma membrane adaptor AP-2 17 kDa protein|sigma2-adaptin
Swissprots P53680 O75977 B2R4Z4 Q6PK67
Accessions EAW57448 EAW57449 P53680 AI139089 AJ010148 CAA09018 AJ010149 CAA09019 AJ713543 AK312003 BAG34941 BC006337 AAH06337 BF970609 BG282225 BI561502 BQ221562 BQ684675 BU564736 CA454481 CB108423 DB472500 H46780 JF432568 ADZ15785 X97074 CAA65782 XM_011526423 XP_011524725 XM_011526424 XP_011524726 NM_001301076 NP_001288005 NM_001301078 NP_001288007 NM_001301081 NP_001288010 NM_004069 NP_004060 NM_021575 NP_067586
Function Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein Transport via Transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin- coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but is itself unable to bind directly to membrane components. Clathrin-associated adaptor protein (AP) complexes which can bind directly to both the clathrin lattice and to the lipid and protein components of membranes are considered to be the major clathrin adaptors contributing the CCV formation. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to p
Subcellular Location Cell membrane. Membrane, coated pit; Peripheral membrane protein; Cytoplasmic side. Note=AP-2 appears to be excluded from internalizing CCVs and to disengage from sites of endocytosis seconds before internalization of the nascent CCV. {ECO:0000250}.
Top Pathways Huntington's disease, Endocytosis, Endocrine and other factor-regulated calcium reabsorption, Synaptic vesicle cycle

Apelin 17, AP17, Human, ELISA Kit - E-EL-H0236 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t
Sensitivity 0.094
Range 0.156-10ng/mL

AP-2 complex subunit sigma (AP2S1), Human, ELISA Kit - E01A1566 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t
Sensitivity 0.1ng/ml
Range 1.0-25ng/ml

Apelin 17 (AP17), Human, ELISA Kit - CED065Hu from ARP American Research Products

Category ELISA Kit
Prices $720.00
Sizes 96 t
Sensitivity 46.2pg/mL
Range 123.5-10,000pg/mL

Apelin 17, AP 17, Rabbit, ELISA Kit - E-EL-RB1096 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Apelin 17, AP 17, Chicken, ELISA Kit - E-EL-Ch2041 from ARP American Research Products

Category ELISA Kit
Prices $522.00
Sizes 96 t

Apelin 17, AP 17, Porcine, ELISA Kit - E-EL-P1751 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

Apelin 17, AP 17, Monkey, ELISA Kit - E-EL-MK0796 from ARP American Research Products

Category ELISA Kit
Prices $585.00
Sizes 96 t

adaptor-related protein complex 2, sigma 1 subunit, ELISA Kit - MBS9340745 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7248896 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7225096 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7236435 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7234156 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7232894 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7213738 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7210429 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7253474 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human AP17(Apelin 17) ELISA Kit - E-EL-H0236 from Elabscience

Category ELISA Kit
Sensitivity 0.10 ng/mL
Range 0.16—10 ng/mL

Human AP17 (Apelin 17) CLIA Kit - E-CL-H0204 from Elabscience

Category CLIA Kit
Sensitivity 0.094ng/mL
Range 0.156~10ng/mL

AP 2 complex subunit sigma (AP2S1), ELISA Kit - MBS7241583 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7231719 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7229676 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP-2 complex subunit sigma (AP2S1), ELISA Kit - MBS7204088 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

AP17, ELISA Kit - MBS2511521 from MyBioSource

Category ELISA Kit
Prices $445.00
Sizes 96 -strip-wells
Sensitivity 0.094ng/mL
Range 0.156--10ng/mL

Human AP17(Apelin 17) ELISA Kit - E-EL-H0236 from Iwai North America Inc.

Category ELISA Kit
Prices $495.00
Sizes 1 kit
Sensitivity 0.1 ng/mL
Range 0.16~10 ng/mL

Human AP17 (Apelin 17) CLIA Kit - E-CL-H0204 from Iwai North America Inc.

Category CLIA Kit
Prices $722.50
Sizes 1 kit
Sensitivity 0.094ng/mL
Range 0.156-10ng/mL
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