MICAL2

Gene Symbol	MICAL2
Entrez Gene	9645
Alt Symbol	MICAL-2, MICAL2PV1, MICAL2PV2
Species	Human
Gene Type	protein-coding
Description	microtubule associated monooxygenase, calponin and LIM domain containing 2
Other Description	flavoprotein oxidoreductase MICAL2|microtubule associated monoxygenase, calponin and LIM domain containing 2|molecule interacting with CasL protein 2|protein-methionine sulfoxide oxidase MICAL2
Swissprots	Q7Z3A8 O94851 G3XAC8 B7Z849 Q5KTR3 B4DGZ0 Q5KTR4 D3DQW5
Accessions	CAG27589 CAG27590 CBB98512 CBB98513 CCQ43448 EAW68528 EAW68529 EAW68530 EAW68531 O94851 AB018293 BAA34470 AB110785 BAD83656 AB110786 BAD83657 AF052170 AK025186 AK026116 AK090550 AK122821 AK125552 AK125785 AK127301 AK294845 BAG57951 AK302580 BAG63835 AK302893 BAH13835 AL046982 BC015755 BC017104 BC044577 AAH44577 BC048206 BC063589 BG939697 BK000462 DAA01341 BX538021 CAD97967 BX641163 CAE46072 DA246062 XM_005253249 XP_005253306 XM_011520490 XP_011518792 XM_011520491 XP_011518793 NM_001282663 NP_001269592 NM_001282664 NP_001269593 NM_001282665 NP_001269594 NM_001282666 NP_001269595 NM_001282667 NP_001269596 NM_001282668 NP_001269597 NM_014632 NP_055447
Function	Nuclear monooxygenase that promotes depolymerization of F-actin by mediating oxidation of specific methionine residues on actin and regulates the SRF signaling. Acts by modifying nuclear actin subunits through the addition of oxygen to form methionine- sulfoxide, leading to promote actin filament severing and prevent repolymerization. Acts as a key regulator of the SRF signaling pathway elicited by nerve growth factor and serum: mediates oxidation and subsequent depolymerization of nuclear actin, leading to increase MKL1/MRTF-A presence in the nucleus and promote SRF:MKL1/MRTF-A-dependent gene transcription. Does not activate SRF:MKL1/MRTF-A through RhoA. {ECO:0000269|PubMed:23927065, ECO:0000269|PubMed:24440334}.
Subcellular Location	Nucleus {ECO:0000269|PubMed:24440334}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human MICAL2 protein fragment - ab160594 from Abcam Category Protein Source Wheat germ Species Human

MICAL2 Antibody Blocking Peptide - LS-E10210 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MICAL2 Antibody Blocking Peptide - LS-E24478 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MICAL2 Antibody Blocking Peptide - LS-E24477 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

MICAL2 Partial Recombinant Protein - H00009645-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

MICAL2-Antibody-N-term-Blocking-Peptide - BP9597a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human MICAL2 protein - orb246761 from Biorbyt Category Protein Prices $340.00, $629.00, $1,003.00, $1,556.00 Sizes 50 μg, 200 μg, 500 μg, 1 mg Species Human

MICAL2 - H00009645-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Species Human

MICAL2 - H00009645-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Species Human

MICAL2 fusion protein - ag4950 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

MICAL2 fusion protein - Ag5318 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

Recombinant Human Protein-methionine sulfoxide oxidase MICAL2(MICAL2) ,partial - CSB-EP013808HU CSB-BP013808HU CSB-MP013808HU from Cusabio Category Protein Source E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human Protein-methionine sulfoxide oxidase MICAL2(MICAL2) ,partial - CSB-YP013808HU from Cusabio Category Protein Source Yeast Species Human

MICAL2 Recombinant Protein Antigen - NBP1-81483PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

MICAL2 Peptide, Human - M34GP09506H from Creative Peptides Category Peptide Source Synthetic. Species Human

MICAL2 Recombinant Protein (OPCA02722) - OPCA02722 from Aviva Systems Biology Category Protein Prices $250.00 Sizes 50 µg Source Human

Recombinant Homo sapiens Protein-methionine sulfoxide oxidase MICAL2 - AP72668 from Signalway Antibody Category Protein Prices $260.00, $735.00, $1,240.00, $1,975.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast

Methionine sulfoxide oxidase MICAL2, Recombinant Protein - MBS9422392 from MyBioSource Category Protein Prices $280.00, $665.00, $1,080.00, $1,690.00 Sizes 50 µg, 200 µg, 500 µg, 1 mg Source Yeast Species Human

Protein-methionine sulfoxide oxidase MICAL2, Recombinant Protein - MBS1146662 from MyBioSource Category Protein Prices $110.00, $190.00, $285.00, $460.00, $750.00, $1,180.00, $1,450.00, $1,605.00, $1,805.00, $2,000.00, $2,100.00, $2,600.00, $2,855.00, $3,560.00 Sizes 10 µg (Yeast), 50 µg (Yeast), 100 µg (Yeast), 200 µg (Yeast), 500 µg (Yeast), 1 mg (Yeast), 50 µg (Baculovirus), 500 µg (E-Coli), 100 µg (Baculovirus), 1 mg (E-Coli), 50 µg (Mammalian-Cell), 100 µg (Mammalian-Cell), 500 µg (Baculovirus), 1 mg (Baculovirus) Source E Coli or Yeast or Baculovirus or Mammalian Cell

Recombinant Human MICAL2 Protein (1-495 aa), His-tagged - MICAL2-1455H from Creative Biomart Category Protein Source Yeast Species Human

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