PRKAG1

Gene Symbol	PRKAG1
Entrez Gene	5571
Alt Symbol	AMPKG
Species	Human
Gene Type	protein-coding
Description	protein kinase, AMP-activated, gamma 1 non-catalytic subunit
Other Description	5'-AMP-activated protein kinase subunit gamma-1|5'-AMP-activated protein kinase, gamma-1 subunit|AMPK gamma-1 chain|AMPK gamma1
Swissprots	P54619 Q8N7V9 B4DDT7
Accessions	EAW58032 EAW58033 P54619 AK097606 BAC05117 AK293332 BAG56848 AK303276 BAG64356 AK307994 AK310250 BC000358 AAH00358 BG772337 BG772412 BI757340 BM667691 BM972308 BT007345 AAP36009 CB124830 DB020277 XM_005269019 XP_005269076 XM_005269020 XP_005269077 XM_006719499 XP_006719562 XM_006719500 XP_006719563 XM_011538562 XP_011536864 NM_001206709 NP_001193638 NM_001206710 NP_001193639 NM_002733 NP_002724 NM_212461
Function	AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating alread
Top Pathways	Non-alcoholic fatty liver disease (NAFLD), Glucagon signaling pathway, AMPK signaling pathway, Oxytocin signaling pathway, Circadian rhythm

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Active human PRKAA2 + PRKAB2 + PRKAG1 full length protein - ab126911 from Abcam Category Protein Prices $410.00 Sizes 5 µg Source Baculovirus infected sf9 cells Species Human

Human AMPK gamma 1 full length protein - ab132975 from Abcam Category Protein Prices $402.00 Sizes 10 µg Source Wheat germ Species Human

Human AMPK gamma 1 full length protein - ab171672 from Abcam Category Protein Prices $297.00 Sizes 50 µg Source E. coli Species Human

Human AMPK gamma 1 peptide - ab87827 from Abcam Category Peptide Prices $176.00 Sizes 100 µg

Human AMPK gamma 1 protein fragment - ab91948 from Abcam Category Protein Prices $119.00 Sizes 20 µg Source E. coli Species Human

PRKAG1 / AMPK Gamma 1 Antibody Blocking Peptide - LS-E1265 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

PRKAG1 / AMPK Gamma 1 Antibody Blocking Peptide - LS-E8642 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

AMPK gamma 1 Recombinant Protein - H00005571-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human AMPK gamma 1 Protein - NBP2-23377 from Novus Biologicals Category Protein Prices $269.00 Sizes 50 µg Source E.coli Species Human

AMPK gamma 1 Peptide - P2145 from Novus Biologicals Category Peptide Species Human

PRKAG1-Antibody-N-term-Blocking-peptide - BP11853a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AMPK-gamma-PRKAG1-Antibody-Center-Blocking-peptide - BP7048c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

PRKAG1 protein (His tag) - 80R-3040 from Fitzgerald Category Protein Prices $275.00 Sizes 50 µg Source E.coli

Human PRKAg1 Protein - abx068763 from Abbexa Category Protein Source E.coli Species Human

AMPK gamma-1 chain / AMPKg (1-331, His-tag) - AR51158PU-N from Acris Antibodies Category Protein Prices $790.00 Sizes 250 µg Source E. coli Species Human

AMPK gamma-1 chain / AMPKg (1-331, His-tag) - AR51158PU-S from Acris Antibodies Category Protein Prices $340.00 Sizes 50 µg Source E. coli Species Human

AMPK gamma-1 chain / AMPKg - H00005571-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

AMPK gamma-1 chain / AMPKg - H00005571-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

PRKAG1, 1-331aa, Human, His tag, E.coli - 01-P2334 from ARP American Research Products Category Protein Prices $149.00, $369.00, $849.00 Sizes 10 µg, 50 µg, 250 µg Species Human

PRKAG1 fusion protein - ag0302 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

PRKAG1, 1-331aa, Human, His tag, E.coli - GWB-ATG517 from Genway Biotech Category Protein Prices $300.00, $900.00 Sizes 50 μg, 250 μg Species Human

Recombinant Human Human Human PRKAA1, His-tagged - PRKAG1-31763TH from Creative Biomart Category Protein

Recombinant Human PRKAG1, His-tagged - PRKAG1-2334H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Protein Kinase, AMP Activated Gamma 1 (PRKAg1) - RPD355Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

AMPK gamma 1 Blocking Peptide - CBP1930 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

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