TYR

Gene Symbol	TYR
Entrez Gene	7299
Alt Symbol	ATN, CMM8, OCA1, OCA1A, OCAIA, SHEP3
Species	Human
Gene Type	protein-coding
Description	tyrosinase
Other Description	LB24-AB|SK29-AB|monophenol monooxygenase|oculocutaneous albinism IA|tumor rejection antigen AB
Swissprots	Q15675 Q9BYY0 Q15680 Q15676 P14679 Q9BZX1 Q8TAK4
Accessions	AAA61242 AAD13985 AAG38762 AAK00805 AGV39051 AGV39052 AGV39053 AGV39055 AGV39056 AGV39057 AGV39058 AGV39059 AGV39060 AGV39061 AGV39062 AGV39063 AGV39064 AGV39065 AGV39066 AGV39067 AGV39068 AGV39069 AGV39070 AGV39071 AGV39072 AGV39073 AGV39074 AGV39075 AGV39076 AGV39077 AGV39078 AGV39079 AGV39080 AGV39081 AGV39085 AGV39088 AGV39093 AGV39094 AGV39097 AGV39098 AGV39099 AGV39100 AGV39101 AGV39103 AGV39105 AGV39106 AGV39107 AGV39108 AGV39109 AGV39110 AGV39111 AGV39112 AGV39113 AGV39114 AGV39115 AGV39116 AGV39117 AGV39118 AGV39119 AGV39120 AGV39121 AGV39124 AGV39125 AGV39126 AGV39127 AGV39128 AGV39129 AGV39130 AGV39131 AGV39133 AGV39134 AGV39135 AGV39136 AGV39137 AGV39138 AGV39139 AGV39140 AGV39141 AGV39142 AGV39143 AGV39144 AGV39145 AGV39146 AGV39147 AGV39148 AGV39149 AGV39150 AGV39151 AGV39152 AGV39153 AGV39154 AGV39155 AGV39156 AGV39157 AGV39158 AGV39159 AGV39160 AGV39161 AGV39163 AGV39169 AGV39174 AGV39177 AGV39178 AGV39179 AGV39180 AGV39181 AGV39182 AGV39183 AGV39184 AGV39185 AGV39186 AGV39187 AGV39189 AGV39190 AGV39191 AGV39193 AGV39195 AGV39196 AGV39197 AGV39198 AGV39199 AGV39200 AGV39201 AGV39202 AGV39203 AGV39204 AGV39205 AGV39206 AGV39207 AGV39208 AGV39209 AGV39210 AHZ44440 CAA34205 EAW59356 EAW59357 P14679 AB775899 BAM75356 AB775900 BAM75357 AB775901 BAM75358 BC027179 AAH27179 BU736025 J03581 AAA61241 M27160 AAB37227 M74314 AAA61244 S66645 AAD13984 U01873 AAB60319 Y00819 CAA68756 XM_011542970 XP_011541272 NM_000372 NP_000363
Function	This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
Subcellular Location	Melanosome membrane {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}; Single-pass type I membrane protein {ECO:0000269|PubMed:12643545, ECO:0000269|PubMed:17081065}.
Top Pathways	Melanogenesis, Tyrosine metabolism, Riboflavin metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

SimpleChIP ® Human Tyrosinase Promoter Primers - 12970 from Cell Signaling Technology Category ChIP Kit Prices $102.00 Sizes 500 µl (250 PCR reactions)

Human Tyrosinase ELISA Kit (Cell-Based ELISA) - LS-F2373 from LifeSpan Bioscience Category ELISA Kit Prices $450.00 Sizes 1 plate Range 15.63-1000 pg/ml

Rat Tyrosinase ELISA Kit (Sandwich ELISA) - LS-F7593 from LifeSpan Bioscience Category ELISA Kit Prices $700.00 Sizes 1 plate Sensitivity 6.7 pg/ml Range 15.63-1000 pg/ml

Human Tyrosinase ELISA Kit (Sandwich ELISA) - LS-F8189 from LifeSpan Bioscience Category ELISA Kit Prices $650.00 Sizes 1 plate Sensitivity 0.259 ng/ml Range 15.63-1000 pg/ml

Bovine Tyrosinase ELISA Kit (Sandwich ELISA) - LS-F9280 from LifeSpan Bioscience Category ELISA Kit Prices $780.00 Sizes 1 plate Sensitivity 3.1 ng/ml Range 15.63-1000 pg/ml

Human Tyrosinase ELISA Kit (Sandwich ELISA) - LS-F12888 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.78 ng/ml Range 15.63-1000 pg/ml

Mouse Tyrosinase ELISA Kit (Sandwich ELISA) - LS-F12887 from LifeSpan Bioscience Category ELISA Kit Prices $600.00 Sizes 1 plate Sensitivity 0.312 Range 15.63-1000 pg/ml

Tyrosinase, TYR, Human, ELISA Kit - E-EL-H1665 from ARP American Research Products Category ELISA Kit Prices $522.00 Sizes 96 t Sensitivity 0.375 Range 0.625-40ng/mL

Tyrosinase (TYR), Human, ELISA Kit - CSB-EL025394HU from ARP American Research Products Category ELISA Kit Prices $495.00, $695.00, $696.00, $699.00 Sizes 48 t, 96 t, 5 x 96t, 10 x 96t Sensitivity 3.9 pg/ml Range 15.6 pg/ml-1000 pg/ml

Tyrosinase (TYR), Human, ELISA Kit - SEA238Hu from ARP American Research Products Category ELISA Kit Prices $650.00 Sizes 96 t Sensitivity OCAIA, OCA1A, OCA1, CMM8, Oculocutaneous Albinism IA Range and sub-band 1 of band 2.

Tyrosinase Antibody, Human, ELISA Kit - YHB3129Hu from ARP American Research Products Category ELISA Kit

Tyrosinase, Human, ELISA Kit - E01T0006 from ARP American Research Products Category ELISA Kit Prices $535.00, $735.00 Sizes 48 t, 96 t Sensitivity 1.0pg/ml Range 100-2500pg/ml

Tyrosinase, TYR, Human, ELISA Kit - E1208h from ARP American Research Products Category ELISA Kit Prices $596.00 Sizes 96 t Range 0.78-50 ng/mL

Tyrosinase, TYR, Mouse, ELISA Kit - E-EL-M1217 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 0.094 Range 0.156-10ng/mL

Tyrosinase, TYR, Rat, ELISA Kit - E-EL-R1045 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t Sensitivity 9.375 Range 15.625-1000pg/mL

Tyrosinase (TYR), Rat, ELISA Kit - SEA238Ra from ARP American Research Products Category ELISA Kit Prices $704.00 Sizes 96 t Sensitivity OCAIA, OCA1A, OCA1, CMM8, Oculocutaneous Albinism IA Range and sub-band 1 of band 2.

Tyrosinase, TYR, Rabbit, ELISA Kit - E-EL-RB2123 from ARP American Research Products Category ELISA Kit Prices $648.00 Sizes 96 t

Tyrosinase, TYR, Chicken, ELISA Kit - E-EL-Ch0564 from ARP American Research Products Category ELISA Kit Prices $504.00 Sizes 96 t

Tyrosinase, TYR, Porcine, ELISA Kit - E-EL-P2011 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Tyrosinase (TYR), Bovine, ELISA Kit - SEA238Bo from ARP American Research Products Category ELISA Kit Prices $776.00 Sizes 96 t Sensitivity OCAIA, OCA1A, OCA1, CMM8, Oculocutaneous Albinism IA Range and sub-band 1 of band 2.

Tyrosinase, TYR, Monkey, ELISA Kit - E-EL-MK0927 from ARP American Research Products Category ELISA Kit Prices $585.00 Sizes 96 t

Human Tyr ELISA Kit - HT0391 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Human Tyr ELISA Kit - HT0013 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Tyr ELISA Kit - AT0013 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Anserine Tyr ELISA Kit - AT0391 from NeoScientific Category ELISA Kit Prices $495.00 Sizes 96 t

Search more