Gene Symbol | ACHE |
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Entrez Gene | 43 |
Alt Symbol | ACEE, ARACHE, N-ACHE, YT |
Species | Human |
Gene Type | protein-coding |
Description | acetylcholinesterase (Yt blood group) |
Other Description | Yt blood group|acetylcholinesterase|apoptosis-related acetylcholinesterase |
Swissprots | Q2M324 A4D2E2 Q9BXP7 B7ZKZ0 Q86TM9 P22303 Q16169 D6W5X7 Q29S23 Q504V3 Q86YX9 Q53F46 |
Accessions | AAA53473 AAC60618 AAK21003 AAP22364 AAP22365 AAU43801 EAL23812 EAL23813 EAW76460 EAW76461 EAW76462 EAW76463 EAW76464 P22303 AF334270 AAO32948 AI831696 AK223443 BAD97163 AK291321 BAF84010 AY389977 AAR26654 BC001541 BC026315 BC036813 AAH36813 BC094752 BC105060 AAI05061 BC105062 AAI05063 BC143469 AAI43470 BG707892 DA205851 M55040 AAA68151 XM_006715995 XP_006716058 XM_011516225 XP_011514527 XM_011516226 XP_011514528 XM_011516227 XP_011514529 XM_011516228 XP_011514530 XM_011516229 XP_011514531 XR_927464 XR_927465 NM_000665 NP_000656 NM_001282449 NP_001269378 NM_001302621 NP_001289550 NM_001302622 NP_001289551 NM_015831 NP_056646 |
Function | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. {ECO:0000269|PubMed:11985878, ECO:0000269|PubMed:1517212, ECO:0000269|PubMed:1748670, ECO:0000269|PubMed:2714437}. |
Subcellular Location | Isoform H: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}. |
Tissue Specificity | Isoform H is highly expressed in erythrocytes. {ECO:0000269|PubMed:2714437}. |
Top Pathways | Glycerophospholipid metabolism |
Acetylcholinesterase peptide (601-614) - ab45700 from Abcam
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Human Acetylcholinesterase full length protein - ab157830 from Abcam
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Human Acetylcholinesterase protein fragment - ab157831 from Abcam
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ACHE / Acetylcholinesterase Antibody Blocking Peptide - LS-E25834 from LifeSpan Bioscience
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ACHE / Acetylcholinesterase Antibody Blocking Peptide - LS-E20656 from LifeSpan Bioscience
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ACHE / Acetylcholinesterase Antibody Blocking Peptide - LS-E20657 from LifeSpan Bioscience
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ACHE / Acetylcholinesterase Antibody Blocking Peptide - LS-E9316 from LifeSpan Bioscience
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Acetylcholinesterase/ACHE Partial Recombinant Protein - H00000043-Q01 from Novus Biologicals
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Recombinant Human Acetylcholinesterase/ACHE Protein - H00000043-P01 from Novus Biologicals
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ACHE-Antibody-N-term-Blocking-Peptide - BP7853a from Abgent, a WuXi AppTec company
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AChE blocking peptide - GTX89580-PEP from GeneTex
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Recombinant Human Acetylcholinesterase/ACHE, CF - 7574-CE-010 from R&D Systems
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ACHE peptide - orb216870 from Biorbyt
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AChE Blocking Peptide - 33R-8642 from Fitzgerald
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AChE Blocking Peptide - 33R-9575 from Fitzgerald
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Acetylcholinesterase Blocking Peptide - abx062201 from Abbexa
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Human Acetylcholinesterase Protein - abx065083 from Abbexa
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Acetylcholinesterase Peptide - AC21-0666-P from Abcore
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Acetylcholinesterase - H00000043-P01-10 from Acris Antibodies
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Acetylcholinesterase - H00000043-P01-25 from Acris Antibodies
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Acetylcholinesterase - H00000043-Q01-10 from Acris Antibodies
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Acetylcholinesterase - H00000043-Q01-25 from Acris Antibodies
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Acetylcholinesterase (AchE), Human - 20-7718 from ARP American Research Products
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ACHE Peptide - 45-193P from ProSci
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ACHE fusion protein - Ag12146 from Proteintech Group
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