ACHE

Gene Symbol	ACHE
Entrez Gene	43
Alt Symbol	ACEE, ARACHE, N-ACHE, YT
Species	Human
Gene Type	protein-coding
Description	acetylcholinesterase (Yt blood group)
Other Description	Yt blood group|acetylcholinesterase|apoptosis-related acetylcholinesterase
Swissprots	Q2M324 A4D2E2 Q9BXP7 B7ZKZ0 Q86TM9 P22303 Q16169 D6W5X7 Q29S23 Q504V3 Q86YX9 Q53F46
Accessions	AAA53473 AAC60618 AAK21003 AAP22364 AAP22365 AAU43801 EAL23812 EAL23813 EAW76460 EAW76461 EAW76462 EAW76463 EAW76464 P22303 AF334270 AAO32948 AI831696 AK223443 BAD97163 AK291321 BAF84010 AY389977 AAR26654 BC001541 BC026315 BC036813 AAH36813 BC094752 BC105060 AAI05061 BC105062 AAI05063 BC143469 AAI43470 BG707892 DA205851 M55040 AAA68151 XM_006715995 XP_006716058 XM_011516225 XP_011514527 XM_011516226 XP_011514528 XM_011516227 XP_011514529 XM_011516228 XP_011514530 XM_011516229 XP_011514531 XR_927464 XR_927465 NM_000665 NP_000656 NM_001282449 NP_001269378 NM_001302621 NP_001289550 NM_001302622 NP_001289551 NM_015831 NP_056646
Function	Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. {ECO:0000269|PubMed:11985878, ECO:0000269|PubMed:1517212, ECO:0000269|PubMed:1748670, ECO:0000269|PubMed:2714437}.
Subcellular Location	Isoform H: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}.
Tissue Specificity	Isoform H is highly expressed in erythrocytes. {ECO:0000269|PubMed:2714437}.
Top Pathways	Glycerophospholipid metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

AChE CRISPR/Cas9 KO Plasmid (h) - sc-401091 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE HDR Plasmid (h) - sc-401091-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE Double Nickase Plasmid (h) - sc-401091-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE Double Nickase Plasmid (h2) - sc-401091-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE CRISPR Activation Plasmid (h) - sc-401091-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE CRISPR Activation Plasmid (h2) - sc-401091-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE Lentiviral Activation Particles (h) - sc-401091-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE Lentiviral Activation Particles (h2) - sc-401091-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE siRNA (h) - sc-29628 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AChE shRNA Plasmid (h) - sc-29628-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

AChE shRNA (h) Lentiviral Particles - sc-29628-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

Acetylcholinesterase/ACHE RNAi - H00000043-R01 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU072891 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN1772 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1772 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

ACHE siRNA (Human) - CRH0034 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

Acetylcholinesterase/ACHE RNAi - H00000043-R02 from Novus Biologicals Category siRNA Prices $409.00 Sizes 20 nmol Species Reactivities Human

ACHE - MBS827105 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ACHE (NM_000665.3) - SHH230266 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ACHE(NM_000665.3) - SHG029431 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ACHE(NM_015831.2) - SHG029449 from Creative biogene Category siRNA Species Reactivities Human

AChE CRISPR/Cas9 KO Plasmid (h2) - sc-401091-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

AChE HDR Plasmid (h2) - sc-401091-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human ACHE siRNA - orb260536 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ACHE shRNA Plasmid (Human) - CHH0034 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

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