Gene Symbol | ACHE |
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Entrez Gene | 43 |
Alt Symbol | ACEE, ARACHE, N-ACHE, YT |
Species | Human |
Gene Type | protein-coding |
Description | acetylcholinesterase (Yt blood group) |
Other Description | Yt blood group|acetylcholinesterase|apoptosis-related acetylcholinesterase |
Swissprots | Q2M324 A4D2E2 Q9BXP7 B7ZKZ0 Q86TM9 P22303 Q16169 D6W5X7 Q29S23 Q504V3 Q86YX9 Q53F46 |
Accessions | AAA53473 AAC60618 AAK21003 AAP22364 AAP22365 AAU43801 EAL23812 EAL23813 EAW76460 EAW76461 EAW76462 EAW76463 EAW76464 P22303 AF334270 AAO32948 AI831696 AK223443 BAD97163 AK291321 BAF84010 AY389977 AAR26654 BC001541 BC026315 BC036813 AAH36813 BC094752 BC105060 AAI05061 BC105062 AAI05063 BC143469 AAI43470 BG707892 DA205851 M55040 AAA68151 XM_006715995 XP_006716058 XM_011516225 XP_011514527 XM_011516226 XP_011514528 XM_011516227 XP_011514529 XM_011516228 XP_011514530 XM_011516229 XP_011514531 XR_927464 XR_927465 NM_000665 NP_000656 NM_001282449 NP_001269378 NM_001302621 NP_001289550 NM_001302622 NP_001289551 NM_015831 NP_056646 |
Function | Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft. Role in neuronal apoptosis. {ECO:0000269|PubMed:11985878, ECO:0000269|PubMed:1517212, ECO:0000269|PubMed:1748670, ECO:0000269|PubMed:2714437}. |
Subcellular Location | Isoform H: Cell membrane {ECO:0000250}; Lipid-anchor, GPI-anchor {ECO:0000250}; Extracellular side {ECO:0000250}. |
Tissue Specificity | Isoform H is highly expressed in erythrocytes. {ECO:0000269|PubMed:2714437}. |
Top Pathways | Glycerophospholipid metabolism |
AChE (H-134) - sc-11409 from Santa Cruz Biotechnology
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AChE (A-11) - sc-373901 from Santa Cruz Biotechnology
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AChE (C-16) - sc-6430 from Santa Cruz Biotechnology
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AChE (N-19) - sc-6431 from Santa Cruz Biotechnology
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Anti-Acetylcholinesterase antibody - ab78228 from Abcam
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Anti-Acetylcholinesterase antibody - ab79816 from Abcam
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Anti-Acetylcholinesterase antibody - ab93487 from Abcam
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Anti-Acetylcholinesterase antibody - ab124275 from Abcam
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Anti-Acetylcholinesterase antibody - ab34936 from Abcam
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Anti-Acetylcholinesterase antibody [12B4] - ab23455 from Abcam
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Anti-Acetylcholinesterase antibody [AE-2] - ab77959 from Abcam
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Anti-Acetylcholinesterase antibody [ZR3] - ab2802 from Abcam
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C331477 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (aa587-611, clone 684CT8.3.4) - LS-C344102 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C122577 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C126519 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (aa601-614) - LS-C54423 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C147691 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C62145 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody - LS-C147689 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (clone AE-2) - LS-C152923 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (aa179-228) - LS-C107765 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (Biotin) - LS-C147690 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (aa359-408) - LS-C107918 from LifeSpan Bioscience
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Anti-ACHE / Acetylcholinesterase Antibody (clone 303630) - LS-C195347 from LifeSpan Bioscience
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