PRPF3

Gene Symbol PRPF3
Entrez Gene 9129
Alt Symbol HPRP3, HPRP3P, PRP3, Prp3p, RP18, SNRNP90
Species Human
Gene Type protein-coding
Description pre-mRNA processing factor 3
Other Description PRP3 pre-mRNA processing factor 3 homolog|U4/U6 small nuclear ribonucleoprotein Prp3|U4/U6 snRNP 90 kDa protein|U4/U6-associated RNA splicing factor|pre-mRNA-splicing factor 3
Swissprots O43395 Q5VT54 O43446 B4DSY9
Accessions EAW53556 O43395 AF001947 AAC09069 AF016370 AAC51926 AK222825 BAD96545 AK297139 BAG59640 AK297265 BAG59740 AK299980 BAG61801 AK309330 AK310241 AK311653 AK312891 BAG35738 BC000184 AAH00184 BC001954 AAH01954 BQ002848 DC407158 DQ892853 ABM83779 DQ896100 ABM87099 XM_011510128 XP_011508430 XM_011510129 XP_011508431 XM_011510130 XP_011508432 XM_011510131 XP_011508433 XM_011510132 XP_011508434 XR_241103 XR_241104 XR_921997 XR_921998 NM_004698 NP_004689
Function Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. {ECO:0000269|PubMed:9328476, ECO:0000269|PubMed:9404889, ECO:0000303|PubMed:20595234}.
Subcellular Location Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Tissue Specificity Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain. {ECO:0000269|PubMed:11773002}.
Top Pathways Spliceosome

PRPF3 (42-N) - sc-101130 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
PRPF3 (42-N): sc-101130. Western blot analysis of PRPF3 expression in HeLa nuclear extract.

PRPF3 (O-23) - sc-102068 from Santa Cruz Biotechnology

Prices $279.00
Sizes 50 µg/0.5 ml
Host Rabbit
Clonality Polyclonal
PRPF3 (O-23): sc-102068. Western blot analysis of PRPF3 expression in Hep G2 whole cell lysate.

PRPF3 (K-14) - sc-131765 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PRPF3 antibody - ab187535 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence analysis of U2OS cells using ab187535. Blue DAPI for nuclear staining.

Anti-PRPF3 antibody - ab56448 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal

Anti-PRPF3 Antibody (aa150-200) - LS-C288831 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PRPF3 Antibody (aa63-112) - LS-C30316 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
A: Marker, B: HepG2 Cell Lysate

Anti-PRPF3 Antibody (C-Terminus) - LS-C345412 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of PRPF3 Antibody with human MCF7 Whole Cell lysate.

Anti-PRPF3 Antibody (clone 4E3) - LS-C179428 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 4E3

Anti-PRPF3 Antibody (aa100-150) - LS-C288830 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Human and Mouse hPrp3p by Immunohistochemistry. Sample: FFPE section of human breast carcinoma (left) and mouse renal cell carcinoma (right). Antibody: Affinity purified rabbit anti-hPrp3p used at a dilution of 1:5000 (0.2and 1:1000 (1 Detection: DAB.

Anti-PRPF3 Antibody (aa100-150) - LS-C286727 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Detection of Mouse hPrp3p Immunohistochemistry. Sample: FFPE section of mouse teratoma. Antibody: Affinity purified rabbit anti-hPrp3p used at a dilution of 1:100.

Anti-PRPF3 Antibody - LS-C334081 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of U20S cell using PRPF3 antibody. Blue: DAPI for nuclear staining.

Anti-PRPF3 Antibody - LS-C341803 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

PRPF3 Antibody - NBP1-19114 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PRPF3 Antibody [NBP1-19114] - FFPE section of mouse teratoma. Affinity purified rabbit anti-hPrp3p used at a dilution of 1:100.

PRPF3 Antibody - NBP1-83219 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PRPF3 Antibody [NBP1-83219] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

PRPF3 Antibody - NBP1-57201 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: PRPF3 Antibody [NBP1-57201] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

PRPF3 Antibody (3H6) - H00009129-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H6
Western Blot: PRPF3 Antibody (3H6) [H00009129-M01] - PRPF3 monoclonal antibody (M01), clone 3H6 Analysis of PRPF3 expression in Hela S3 NE.

PRPF3 Antibody (3H6) - H00009129-M01A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3H6

Anti-PRPF3 antibody produced in rabbit - HPA027226 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PRPF3: <B>Cat. No. HPA027226</B>: Immunohistochemical staining of human skeletal muscle shows strong cytoplasmic positivity in subsets of muscle fibers.

Anti-PRPF3 antibody produced in rabbit - AV40543 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV40543</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 0.5 μg/mL in cell type HepG2

Monoclonal Anti-PRPF3 antibody produced in mouse - WH0009129M1 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone 3H6
<B>Immunoblotting</B><BR/>Monoclonal Anti-PRPF3, <B>Cat. No. WH0009129M1</B> used at the antibody concentration: 1 ~ 5 μg/mL. Specific band of ~77.5 kDa using Hela NE lysate.

PRPF3 antibody - N-terminal region (ARP40543_P050) - ARP40543_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PRPF3 Antibody - C-terminal region (ARP40544_P050) - ARP40544_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PRPF3-Antibody-monoclonal-M01 - AT3442a from Abgent, a WuXi AppTec company

Prices $315.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3H6
Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.63 KDa) .

PRPF3 antibody - 70R-4686 from Fitzgerald

Prices $345.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
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