PRPF3

Gene Symbol PRPF3
Entrez Gene 9129
Alt Symbol HPRP3, HPRP3P, PRP3, Prp3p, RP18, SNRNP90
Species Human
Gene Type protein-coding
Description pre-mRNA processing factor 3
Other Description PRP3 pre-mRNA processing factor 3 homolog|U4/U6 small nuclear ribonucleoprotein Prp3|U4/U6 snRNP 90 kDa protein|U4/U6-associated RNA splicing factor|pre-mRNA-splicing factor 3
Swissprots O43395 Q5VT54 O43446 B4DSY9
Accessions EAW53556 O43395 AF001947 AAC09069 AF016370 AAC51926 AK222825 BAD96545 AK297139 BAG59640 AK297265 BAG59740 AK299980 BAG61801 AK309330 AK310241 AK311653 AK312891 BAG35738 BC000184 AAH00184 BC001954 AAH01954 BQ002848 DC407158 DQ892853 ABM83779 DQ896100 ABM87099 XM_011510128 XP_011508430 XM_011510129 XP_011508431 XM_011510130 XP_011508432 XM_011510131 XP_011508433 XM_011510132 XP_011508434 XR_241103 XR_241104 XR_921997 XR_921998 NM_004698 NP_004689
Function Participates in pre-mRNA splicing. Part of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. {ECO:0000269|PubMed:9328476, ECO:0000269|PubMed:9404889, ECO:0000303|PubMed:20595234}.
Subcellular Location Nucleus speckle. Note=Colocalizes with spliceosomal snRNPs.
Tissue Specificity Highly expressed in retina, liver, kidney and blood. Detected at lower levels in heart and brain. {ECO:0000269|PubMed:11773002}.
Top Pathways Spliceosome

PRPF3 CRISPR/Cas9 KO Plasmid (h) - sc-409733 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 HDR Plasmid (h) - sc-409733-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 Double Nickase Plasmid (h) - sc-409733-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 Double Nickase Plasmid (h2) - sc-409733-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 CRISPR Activation Plasmid (h) - sc-409733-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 CRISPR Activation Plasmid (h2) - sc-409733-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 Lentiviral Activation Particles (h) - sc-409733-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 Lentiviral Activation Particles (h2) - sc-409733-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

PRPF3 siRNA (h) - sc-88819 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRPF3 shRNA Plasmid (h) - sc-88819-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRPF3 shRNA (h) Lentiviral Particles - sc-88819-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

PRPF3 RNAi - H00009129-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

MISSION® esiRNA - EHU024431 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN17472 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND17472 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR01620 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr01620

PRPF3 siRNA (Human) - CRH6036 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human PRPF3 (NM_004698.2) - SHH383716 from Creative biogene

Category siRNA
Species Reactivities Human

Human PRPF3 siRNA - orb266538 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

PRPF3 shRNA Plasmid (Human) - CHH6036 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

PRPF3 miRNA 3'UTR clone - MiUTR3H-09126 from Creative biogene

Species Reactivities Human
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