Gene Symbol | AMN |
---|---|
Entrez Gene | 81693 |
Alt Symbol | PRO1028, amnionless |
Species | Human |
Gene Type | protein-coding |
Description | amnion associated transmembrane protein |
Other Description | amnionless homolog|protein amnionless|visceral endoderm-specific type 1 transmembrane protein |
Swissprots | Q9BXJ7 Q6UX83 |
Accessions | EAW81798 EAW81799 Q9BXJ7 AF328788 AAK28532 AK055802 BAG51576 AY358468 AAQ89949 BC029948 CB306421 XM_011537202 XP_011535504 XM_011537203 XP_011535505 NM_030943 NP_112205 |
Function | Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:12590260, ECO:0000269|PubMed:14576052}. |
Amnionless CRISPR/Cas9 KO Plasmid (h) - sc-407657 from Santa Cruz Biotechnology
|
||||||||
Amnionless HDR Plasmid (h) - sc-407657-HDR from Santa Cruz Biotechnology
|
||||||||
Amnionless Double Nickase Plasmid (h) - sc-407657-NIC from Santa Cruz Biotechnology
|
||||||||
Amnionless Double Nickase Plasmid (h2) - sc-407657-NIC-2 from Santa Cruz Biotechnology
|
||||||||
Amnionless CRISPR Activation Plasmid (h) - sc-407657-ACT from Santa Cruz Biotechnology
|
||||||||
Amnionless CRISPR Activation Plasmid (h2) - sc-407657-ACT-2 from Santa Cruz Biotechnology
|
||||||||
Amnionless Lentiviral Activation Particles (h) - sc-407657-LAC from Santa Cruz Biotechnology
|
||||||||
Amnionless Lentiviral Activation Particles (h2) - sc-407657-LAC-2 from Santa Cruz Biotechnology
|
||||||||
Amnionless siRNA (h) - sc-60069 from Santa Cruz Biotechnology
|
||||||||
Amnionless shRNA Plasmid (h) - sc-60069-SH from Santa Cruz Biotechnology
|
||||||||
Amnionless shRNA (h) Lentiviral Particles - sc-60069-V from Santa Cruz Biotechnology
|
||||||||
MISSION® esiRNA - EHU150501 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN3119 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3119 from Sigma-Aldrich
|
||||||||
AMN siRNA (Human) - CRJ3042 from Cohesion Biosciences
|
||||||||
AMN - MBS8226689 from MyBioSource
|
||||||||
shRNA set against Human Amn (NM_030943.3) - SHH235834 from Creative biogene
|
||||||||
Human AMN siRNA - orb273543 from Biorbyt
|
||||||||
AMN shRNA Plasmid (Human) - CHJ3042 from Cohesion Biosciences
|
||||||||
AMN miRNA 3'UTR clone - MiUTR3H-07969 from Creative biogene
|