Gene Symbol | AMN |
---|---|
Entrez Gene | 81693 |
Alt Symbol | PRO1028, amnionless |
Species | Human |
Gene Type | protein-coding |
Description | amnion associated transmembrane protein |
Other Description | amnionless homolog|protein amnionless|visceral endoderm-specific type 1 transmembrane protein |
Swissprots | Q9BXJ7 Q6UX83 |
Accessions | EAW81798 EAW81799 Q9BXJ7 AF328788 AAK28532 AK055802 BAG51576 AY358468 AAQ89949 BC029948 CB306421 XM_011537202 XP_011535504 XM_011537203 XP_011535505 NM_030943 NP_112205 |
Function | Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity). {ECO:0000250}. |
Subcellular Location | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
Tissue Specificity | Long isoforms are highly expressed in small intestine, colon and kidney (renal proximal tubule epithelial cells). Shorter isoforms are detected at lower levels in testis, thymus and peripheral blood leukocytes. {ECO:0000269|PubMed:12590260, ECO:0000269|PubMed:14576052}. |
Amnionless (C-10) - sc-365384 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (F-7) - sc-365734 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (H-280) - sc-135178 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (K-14) - sc-46726 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (M-228) - sc-135179 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (N-15) - sc-46729 from Santa Cruz Biotechnology
|
||||||||||
Amnionless (N-16) - sc-46730 from Santa Cruz Biotechnology
|
||||||||||
Anti-AMN antibody - ab105806 from Abcam
|
||||||||||
Anti-AMN antibody [EPR12015(B)] - ab170893 from Abcam
|
||||||||||
Anti-AMN Antibody (aa35-84) - LS-C135239 from LifeSpan Bioscience
|
||||||||||
Amnionless/AMN Antibody (260808) - MAB1860 from Novus Biologicals
|
||||||||||
Amnionless/AMN Antibody - AF1860 from Novus Biologicals
|
||||||||||
Amnionless/AMN Antibody - NBP1-91203 from Novus Biologicals
|
||||||||||
Amnionless/AMN Antibody [Biotin] - BAF1860 from Novus Biologicals
|
||||||||||
Anti-AMN, (N-terminal) antibody produced in rabbit - SAB2105739 from Sigma-Aldrich
|
||||||||||
Anti-AMN antibody produced in rabbit - HPA000817 from Sigma-Aldrich
|
||||||||||
AMN antibody - N-terminal region (ARP49982_P050) - ARP49982_P050 from Aviva Systems Biology
|
||||||||||
Mouse Amnionless Antibody - AF7139 from R&D Systems
|
||||||||||
Mouse Amnionless Affinity Purified Polyclonal Ab, Sheep IgG - AF7139-SP from R&D Systems
|
||||||||||
Human Amnionless Antibody - AF1860 from R&D Systems
|
||||||||||
Human Amnionless Affinity Purified Polyclonal Ab, Goat IgG - AF1860-SP from R&D Systems
|
||||||||||
Human Amnionless Biotinylated Antibody - BAF1860 from R&D Systems
|
||||||||||
Human Amnionless Antibody - MAB1860 from R&D Systems
|
||||||||||
Human Amnionless MAb (Clone 260808), Mouse IgG1 - MAB1860-SP from R&D Systems
|
||||||||||
AMN antibody - 70R-8847 from Fitzgerald
|