ST8SIA1

Gene Symbol ST8SIA1
Entrez Gene 6489
Alt Symbol GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI
Species Human
Gene Type protein-coding
Description ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Other Description alpha-2,8-sialyltransferase 8A|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase|disialoganglioside (GD3) synthase|ganglioside GD3 synthase|ganglioside GT3 synthase|ganglioside-specific alpha-2,8-polysialyltransferase|sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A|sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase)|sialyltransferase St8Sia I|sialytransferase St8Sia I
Swissprots Q93064 Q92185 Q17RL0 A8K4H6 Q6PZN5
Accessions CAS91695 EAW96468 EAW96469 EAW96470 EAW96471 Q92185 AF088002 AK290941 BAF83630 AK297310 BAG59776 AK315340 BAG37739 AY569975 AAS75783 BC031081 BC046158 AAH46158 BC117285 AAI17286 BC126162 AAI26163 BM929838 D26360 BAA05391 EU041716 ABU62753 HQ258201 ADR82955 L32867 AAA62366 L43494 AAC37586 X77922 CAA54891 XM_005253470 XP_005253527 XM_011520817 XP_011519119 XR_931322 NM_001304450 NP_001291379 NM_003034 NP_003025
Function Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8058740, ECO:0000269|PubMed:8195250, ECO:0000269|PubMed:8631981}.
Subcellular Location Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8631981}.
Top Pathways Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - ganglio series

ST8SIA1 overexpression lysate - LY401062 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

ST8SIA1 293 Cell Lysate - 400995 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Overexpression Lysate (Native) - NBL1-16505 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: Ganaglioside GD3 Overexpression Lysate (Adult Normal) [NBL1-16505] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Ganaglioside GD3.

ST8SIA1 Over-expression Lysate Product - GWB-ABA56C from Genway Biotech

Category Cell Lysate
Prices $445.00
Sizes 100 µg
Species Human

Human ST8SIA1 / GD3S HEK293 Cell Lysate (WB positive control) - 15646-H08HL-300 from Sino Biological

Category Cell Lysate
Prices $195.00
Sizes 300 µg
Species Human

Human ST8SIA1 Human Cells Transfected Lysate (positive control) (denatured) - orb233040 from Biorbyt

Category Cell Lysate
Prices $425.00
Sizes 300 μg
Species Human

Panoply™ Human ST8SIA1 Knockdown Stable Cell Line - CSC-DC015250 from Creative biogene

Category Cell Line
Species Human
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