ST8SIA1

Gene Symbol	ST8SIA1
Entrez Gene	6489
Alt Symbol	GD3S, SIAT8, SIAT8-A, SIAT8A, ST8SiaI
Species	Human
Gene Type	protein-coding
Description	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Other Description	alpha-2,8-sialyltransferase 8A|alpha-N-acetylneuraminide alpha-2,8-sialyltransferase|disialoganglioside (GD3) synthase|ganglioside GD3 synthase|ganglioside GT3 synthase|ganglioside-specific alpha-2,8-polysialyltransferase|sialyltransferase 8 (alpha-N-acetylneuraminate: alpha-2,8-sialytransferase, GD3 synthase) A|sialyltransferase 8A (alpha-N-acetylneuraminate: alpha-2,8-sialyltransferase, GD3 synthase)|sialyltransferase St8Sia I|sialytransferase St8Sia I
Swissprots	Q93064 Q92185 Q17RL0 A8K4H6 Q6PZN5
Accessions	CAS91695 EAW96468 EAW96469 EAW96470 EAW96471 Q92185 AF088002 AK290941 BAF83630 AK297310 BAG59776 AK315340 BAG37739 AY569975 AAS75783 BC031081 BC046158 AAH46158 BC117285 AAI17286 BC126162 AAI26163 BM929838 D26360 BAA05391 EU041716 ABU62753 HQ258201 ADR82955 L32867 AAA62366 L43494 AAC37586 X77922 CAA54891 XM_005253470 XP_005253527 XM_011520817 XP_011519119 XR_931322 NM_001304450 NP_001291379 NM_003034 NP_003025
Function	Involved in the production of gangliosides GD3 and GT3 from GM3; gangliosides are a subfamily of complex glycosphinglolipds that contain one or more residues of sialic acid. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8058740, ECO:0000269|PubMed:8195250, ECO:0000269|PubMed:8631981}.
Subcellular Location	Golgi apparatus membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Tissue Specificity	Strongly expressed in melanoma cell lines, adult and fetal brain and to a lesser extent in adult and fetal lung. {ECO:0000269|PubMed:7937974, ECO:0000269|PubMed:8631981}.
Top Pathways	Glycosphingolipid biosynthesis - globo series, Glycosphingolipid biosynthesis - lacto and neolacto series, Glycosphingolipid biosynthesis - ganglio series

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human ST8SIA1 protein fragment - ab116781 from Abcam Category Protein Source Wheat germ Species Human

Recombinant Human ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Protein - H00006489-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

Recombinant Human ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Protein - H00006489-G01-10ug from Novus Biologicals Category Protein Prices $569.00 Sizes 10 µg Species Human

Recombinant Human ST8SIA1, CF - 6716-GT-020 from R&D Systems Category Protein Source Chinese Hamster Ovary cell line, CHO-derived, Tyr49-Ser356, with an N-terminal human CD33 signal peptide and a C-terminal 6‑His tag

Human ST8SIA1 (His Tag) protein - orb232382 from Biorbyt Category Protein Prices $400.00, $816.00 Sizes 20 μg, 100 μg Species Human

Human ST8SIA1, alpha protein - orb180349 from Biorbyt Category Protein Prices $408.00, $595.00, $1,904.00, $2,695.00 Sizes 10 μg, 50 μg, 500 μg, 1 mg Source HEK293 Species Human

ST8SIA1 - H00006489-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

ST8SIA1 - H00006489-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

ST8SIA1 fusion protein - ag20497 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

ST8SIA1 fusion protein - ag20429 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human ST8SIA1 - ST8SIA1-30852TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human ST8SIA1, His-tagged - ST8SIA1-2982H from Creative Biomart Category Protein Source E.coli Species Human

Human ST8SIA1 / GD3S Protein (His Tag) - 15646-H08H-20 from Sino Biological Category Protein Prices $178.00, $178.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

Recombinant Human Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase(ST8SIA1) - CSB-YP838738HU CSB-EP838738HU CSB-BP838738HU CSB-MP838738HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Recombinant Human ST8SIA1 Protein, CF - 6716-GT from R&D Systems Category Protein Prices $359.00 Sizes 20 µg Source Chinese Hamster Ovary cell line, CHO-derived Tyr49-Ser356, with an N-terminal human CD33 signal peptide and a C-terminal 6‑His tag Species Human

Recombinant Human ST8SIA1 (carrier-free) - 750802 from Biolegend Category Protein Prices $165.00, $305.00, $765.00 Sizes 10 µg, 25 µg, 100 µg Source Human ST8SIA1, amino acids (Tyr49-Ser356) (Accession# NP_003025.1), was expressed with a C-terminal His tag in the 293E cell line. Species Human

Alpha-N-acetylneuraminide alpha-2,8-sialyltransferase (ST8SIA1) - MBS1165958 from MyBioSource Category Protein Prices $1,735.00, $2,190.00 Sizes 1 mg (E Coli Derived), 1 mg (Yeast Derived) Source E Coli or Yeast Species Chimpanzee

ST8SIA1 - TP720711 from Acris Antibodies Category Protein Prices $139.00 Sizes 10 µg Source HEK293 cells Species Human

Recombinant Human ST8SIA1 Protein, His-tagged - ST8SIA1-707H from Creative Biomart Category Protein Source HEK293 Species Human

ST8 alpha-2,8-Sialyltransferase 8A/ST8SIA1/Ganglioside GD3 Recombinant Protein Antigen - NBP1-80750PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

ST8SIA1 Peptide, Human - M34GP15250H from Creative Peptides Category Peptide Source Synthetic. Species Human

Human ST8SIA1 / GD3S Protein (His Tag) - 15646-H08H from ABclonal Category Protein Prices $178.00, $448.00 Sizes 20 µg, 100 µg Source Human Cells Species Human

ST8SIA1 Recombinant Protein - 91-569 from ProSci Category Protein Prices $525.00 Sizes 50 µg Source Human Cells Species Human

ST8SIA1, Recombinant Protein - MBS8249830 from MyBioSource Category Protein Prices $255.00, $635.00, $2,370.00 Sizes 10 µg, 50 µg, 500 µg Source Human cells Species Human

Recombinant Human ST8SIA1 Protein, CF - 6716-GT from Novus Biologicals Category Protein Prices $359.00 Sizes 20 µg Species Human

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